Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | SCN9A | Q15858 | 10/20 | 0.42 |
| ▸ | IKBKB | O14920 | 1/20 | 0.38 |
| ▸ | RPS6KA2 | Q15349 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | RORC | P51449 | 1/20 | 0.36 |
| ▸ | SCN10A | Q9Y5Y9 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7052699 | 0.90 | IKBKB (0.45) | ALDH1A1L3MBTL1IKBKBLMNARECQL | |
| SCHEMBL7050095 | 0.86 | MKNK2 (0.40) | ALDH1A1L3MBTL1IKBKBLMNARECQL | |
| SCHEMBL7054012 | 0.84 | IKBKB (0.39) | ALDH1A1L3MBTL1IKBKBLMNARECQL | |
| SCHEMBL7051176 | 0.83 | PDE4A (0.41) | ALDH1A1L3MBTL1IKBKBLMNARECQL | |
| SCHEMBL7056652 | 0.82 | SLC9A1 (0.37) | ALDH1A1L3MBTL1IKBKBLMNARECQL | |
| O-Tolylamine SCHEMBL7366469 | 0.79 | IKBKB (0.38) | ALDH1A1L3MBTL1IKBKBLMNARECQL | |
| SCHEMBL7402562 | 0.78 | CYP1A1 (0.39) | ALDH1A1L3MBTL1IKBKBLMNARECQL | |
| SCHEMBL7055258 | 0.77 | PDE4A (0.45) | ALDH1A1L3MBTL1IKBKBLMNARECQL | |
| SCHEMBL7055267 | 0.77 | LMNA (0.40) | ALDH1A1LMNARECQL | |
| SCHEMBL7051106 | 0.76 | IKBKB (0.41) | ALDH1A1L3MBTL1IKBKBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0901482-B1 | BENZOFURAN CARBOXAMIDES AND THEIR THERAPEUTIC USE | DARWIN DISCOVERY LTD (GB) | 2003-05-02 | — | — | EP | disclosed |