SCHEMBL705236

SCHEMBL705236

CCC(c1ccccc1)(c1ccccc1)C(C)O[SiH3]

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GRIN1 Q05586 6/20 0.39
GRIN2A Q12879 6/20 0.39
GRIN2D O15399 5/20 0.39
GRIN2C Q14957 5/20 0.39
GRIN2B Q13224 4/20 0.39
KCNH2 Q12809 2/20 0.36
KCNN4 O15554 1/20 0.35
MAPK1 P28482 1/20 0.34
ALDH1A1 P00352 2/20 0.33
CYP2D6 P10635 1/20 0.33
CYP2C19 P33261 1/20 0.33
HSD17B10 Q99714 1/20 0.33
TAAR1 Q96RJ0 1/20 0.32
ALOX15 P16050 1/20 0.32
OPRM1 P35372 2/20 0.32
KIF11 P52732 1/20 0.32
CACNA1F O60840 1/20 0.32
ABCB1 P08183 1/20 0.32
CYP2B6 P20813 1/20 0.32
DRD4 P21917 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL702333 0.79 KCNH2 (0.44) GRIN1GRIN2AGRIN2DGRIN2CGRIN2B
SCHEMBL6284917 0.77 GRIN1 (0.44) GRIN1GRIN2AGRIN2DGRIN2CGRIN2B
SCHEMBL702749 0.77 KCNH2 (0.37) GRIN1GRIN2AGRIN2DGRIN2CGRIN2B
SCHEMBL109172 0.74 MAPK1 (0.43) KCNN4MAPK1ALDH1A1CYP2D6CYP2C19
SCHEMBL708760 0.74 MAPK1 (0.43) KCNN4MAPK1ALDH1A1CYP2D6CYP2C19
SCHEMBL12809670 0.74 GRIN1 (0.42) GRIN1GRIN2AGRIN2DGRIN2CGRIN2B
SCHEMBL4454908 0.71 GRIN1 (0.43) GRIN1GRIN2AGRIN2DGRIN2CGRIN2B
SCHEMBL416118 0.71 GRIN1 (0.47) GRIN1GRIN2AGRIN2DGRIN2CGRIN2B
SCHEMBL1317834 0.71 GRIN1 (0.37) GRIN1GRIN2AGRIN2DGRIN2CGRIN2B
SCHEMBL1314752 0.70 GRIN1 (0.41) GRIN1GRIN2AGRIN2DGRIN2CGRIN2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9546237-B2 Stabilization of polymers that contain a hydrolyzable functionality BRIDGESTONE CORPORATION (JP) 2017-01-17 US disclosed
US-20130331520-A1 STABILIZATION OF POLYMERS THAT CONTAIN A HYDROLYZABLE FUNCTIONALITY BRIDGESTONE CORPORATION (JP) 2013-12-12 US disclosed
US-8124239-B2 Silica film forming material, silica film and method of manufacturing the same, multilayer wiring structure and method of manufacturing the same, and semiconductor device and method of manufacturing the same FUJITSU LIMITED (JP) 2012-02-28 US disclosed
US-20100155121-A1 SILICA FILM FORMING MATERIAL, SILICA FILM AND METHOD OF MANUFACTURING THE SAME, MULTILAYER WIRING STRUCTURE AND METHOD OF MANUFACTURING THE SAME, AND SEMICONDUCTOR DEVICE AND METHOD OF MANUFACTURING THE SAME FUJITSU LIMITED (JP) 2010-06-24 US disclosed
US-7659357-B2 Precursor organosilicon polymer of 1,2-Bis(dimethylethoxysilyl)ethane, 1,4-bis(dimethylethoxysilyl)benzene, tetraethoxysilane, methyltriethoxysilane, phenyltriethoxysilane; dielectric (DE) films having etching/chemical/moisture resistance; adhesion; low DE constant; minimal wiring delay; high speed FUJITSU LIMITED (JP) 2010-02-09 US disclosed
US-20070026689-A1 Silica film forming material, silica film and method of manufacturing the same, multilayer wiring structure and method of manufacturing the same, and semiconductor device and method of manufacturing the same FUJITSU LIMITED (JP) 2007-02-01 US disclosed
US-5439746-A Formed by coating or impregnating a reinforcement sheet and curing; mechanical strength; corrosion and heat resistance; electrical properties KABUSHIKI KAISHA TOSHIBA (JP) 1995-08-08 US disclosed