SCHEMBL4454908

SCHEMBL4454908

CCC(CC)C(CC)(c1ccccc1)c1ccccc1

nearest known ligand 0.46

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
GRIN1 Q05586 4/20 0.43
GRIN2A Q12879 4/20 0.43
GRIN2D O15399 3/20 0.43
GRIN2C Q14957 3/20 0.43
GRIN2B Q13224 2/20 0.43
KCNN4 O15554 3/20 0.40
KIF11 P52732 2/20 0.40
LMNA P02545 1/20 0.37
TAAR1 Q96RJ0 1/20 0.37
KCNH2 Q12809 1/20 0.36
MEN1 O00255 1/20 0.36
TTR P02766 1/20 0.36
KMT2A Q03164 1/20 0.36
MAPK1 P28482 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17241924 0.85 GRIN1 (0.37) GRIN1GRIN2AGRIN2DGRIN2CGRIN2B
SCHEMBL6284917 0.79 GRIN1 (0.44) GRIN1GRIN2AGRIN2DGRIN2CGRIN2B
SCHEMBL416118 0.77 GRIN1 (0.47) GRIN1GRIN2AGRIN2DGRIN2CGRIN2B
SCHEMBL6552914 0.77 KCNN4 (0.40) GRIN1GRIN2AGRIN2DGRIN2CGRIN2B
SCHEMBL27089593 0.77 GRIN1 (0.40) GRIN1GRIN2AGRIN2DGRIN2CGRIN2B
SCHEMBL1058675 0.76 LMNA (0.40) GRIN1GRIN2AGRIN2DGRIN2CGRIN2B
SCHEMBL1058678 0.76 LMNA (0.40) GRIN1GRIN2AGRIN2DGRIN2CGRIN2B
SCHEMBL9064416 0.76 TAAR1 (0.40) GRIN1GRIN2AGRIN2DGRIN2CGRIN2B
SCHEMBL12809670 0.76 GRIN1 (0.42) GRIN1GRIN2AGRIN2DGRIN2CGRIN2B
SCHEMBL702333 0.74 KCNH2 (0.44) GRIN1GRIN2AGRIN2DGRIN2CGRIN2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7605207-B2 Heat resistance; using with polystyrene fthermoplastic foams BROMINE COMPOUNDS LTD. (IL) 2009-10-20 US claimed
US-20080281024-A1 Flame Retardant Bromobenzyl Systems BROMINE COMPOUNDS LTD. (IL) 2008-11-13 US claimed
EP-1951798-A2 FLAME RETARDANT BROMOBENZYL SYSTEMS Bromine Compounds Ltd. (IL) 2008-08-06 EP claimed
WO-2007057900-A2 FLAME RETARDANT BROMOBENZYL SYSTEMS BROMINE COMPOUNDS LTD. (IL) 2007-05-24 WO claimed
US-7605207-B2 Heat resistance; using with polystyrene fthermoplastic foams BROMINE COMPOUNDS LTD. (IL) 2009-10-20 US disclosed
US-7585912-B2 Flame-retardant polystyrenes BROMINE COMPOUNDS LTD. (IL) 2009-09-08 US disclosed
EP-1786853-B1 NOVEL FLAME-RETARDANT POLYSTYRENES BROMINE COMPOUNDS LTD (IL) 2009-04-15 EP disclosed
US-20080281024-A1 Flame Retardant Bromobenzyl Systems BROMINE COMPOUNDS LTD. (IL) 2008-11-13 US disclosed
EP-1951798-A2 FLAME RETARDANT BROMOBENZYL SYSTEMS Bromine Compounds Ltd. (IL) 2008-08-06 EP disclosed
US-20070257241-A1 Novel Flame-Retardant Polystyrenes BROMINE COMPOUNDS LTD. (IL) 2007-11-08 US disclosed
WO-2007057900-A2 FLAME RETARDANT BROMOBENZYL SYSTEMS BROMINE COMPOUNDS LTD. (IL) 2007-05-24 WO disclosed
EP-1786853-A1 NOVEL FLAME-RETARDANT POLYSTYRENES Bromine Compounds Ltd. (IL) 2007-05-23 EP disclosed
WO-2006013554-A1 NOVEL FLAME-RETARDANT POLYSTYRENES BROMINE COMPOUNDS LTD. (IL) 2006-02-09 WO disclosed
EP-0282064-B1 METHOD FOR PRODUCING M-ETHYLDIPHENYLS NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) 1991-10-23 EP disclosed
US-4835337-A Method for producing m-ethyldiphenyls NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) 1989-05-30 US disclosed
EP-0282064-A1 Method for producing m-ethyldiphenyls NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) 1988-09-14 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080281024-A1 Flame Retardant Bromobenzyl Systems PBRM1, PFAS, BPTF GRIN1 4563/4885GRIN2A 3636/4885GRIN2D 3743/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.