Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | NOS2 | P35228 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3967035 | 0.82 | KDM4E (0.56) | HRH4ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL1145111 | 0.78 | LMNA (0.48) | HRH4ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL10371014 | 0.78 | L3MBTL1 (0.55) | HRH4ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL22917964 | 0.77 | L3MBTL1 (0.41) | HRH4ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL21222984 | 0.77 | MBOAT4 (0.46) | HRH4ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL30242158 | 0.77 | MBOAT4 (0.46) | HRH4ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL15831950 | 0.75 | ALDH1A1 (0.50) | ALDH1A1KDM4EMEN1KMT2AGPR119 | |
| SCHEMBL15831920 | 0.75 | L3MBTL1 (0.43) | HRH4ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL15831917 | 0.74 | MAP3K7 (0.46) | MEN1KMT2AL3MBTL1HDAC1SMN1; SMN2 | |
| SCHEMBL15831912 | 0.74 | GAA (0.42) | ALDH1A1KDM4EMEN1KMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1304325-A1 | 5-(M-CYANOBENZYLAMINO)PYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-04-23 | — | — | EP | disclosed |