SCHEMBL7052372

SCHEMBL7052372

CCCC(=O)N1CCCC1C(=O)O

nearest known ligand 0.64

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ACE P12821 8/20 0.64
REN P00797 3/20 0.54
LMNA P02545 2/20 0.51
HSD17B10 Q99714 2/20 0.51
CYP2C19 P33261 1/20 0.51
KDM4E B2RXH2 1/20 0.51
F2 P00734 1/20 0.51
LTA4H P09960 1/20 0.51
MAPT P10636 1/20 0.51
PEPD P12955 1/20 0.51
ALOX15 P16050 1/20 0.51
PTGS1 P23219 1/20 0.51
HTR2A P28223 1/20 0.51
PTGS2 P35354 1/20 0.51
HRH1 P35367 1/20 0.51
THPO P40225 1/20 0.51
PMP22 Q01453 1/20 0.51
ACE2 Q9BYF1 1/20 0.51
RAB9A P51151 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7052375 1.00 ACE (0.64) ACERENLMNAHSD17B10CYP2C19
SCHEMBL10537366 1.00 ACE (0.64) ACERENLMNAHSD17B10CYP2C19
SCHEMBL19024772 0.90 ACE (0.60) ACERENMAPTACE2
SCHEMBL11742911 0.90 ACE (0.60) ACERENMAPTACE2
SCHEMBL21671042 0.89 ACE (0.50) ACERENLMNAHSD17B10CYP2C19
SCHEMBL6782705 0.89 ACE (0.72) ACEREN
SCHEMBL6782701 0.89 ACE (0.72) ACEREN
SCHEMBL5035730 0.88 ACE (0.59) ACERENACE2
SCHEMBL5033213 0.88 ACE (0.59) ACERENACE2
SCHEMBL5035727 0.88 ACE (0.59) ACERENACE2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0416282-B1 Microbiologically produced N-Acyl-L-proline-acylase, process for its production and its use DEGUSSA (DE) 1994-09-14 EP claimed
EP-0416282-A1 Microbiologically produced N-Acyl-L-proline-acylase, process for its production and its use Degussa Aktiengesellschaft (DE) 1991-03-13 EP claimed
US-4859653-A Use of compositions of matter containing N-acylates of alpha aminoacids for the treatment of skin MORELLE JEAN V (FR) 1989-08-22 US claimed
CN-120077040-A Compounds for SHP2 protein degradation and medical uses thereof 尤比克斯治疗公司 2025-05-30 CN disclosed
US-20250000948-A1 SOLID COMPOSITIONS COMPRISING A PEPTIDE OR A PROTEIN AND AN ACYLATED AMINO ACID ADOCIA (FR) 2025-01-02 US disclosed
EP-4299057-A1 SOLID COMPOSITIONS COMPRISING A PEPTIDE OR A PROTEIN AND AN ACYLATED AMINO ACID Adocia (FR) 2024-01-03 EP disclosed
WO-2023084118-A1 SOLID COMPOSITIONS COMPRISING A PEPTIDE OR A PROTEIN AND AN ACYLATED AMINO ACID ADOCIA (FR) 2023-05-19 WO disclosed
EP-4180060-A1 SOLID COMPOSITIONS COMPRISING A PEPTIDE OR A PROTEIN AND AN ACYLATED AMINO ACID Adocia (FR) 2023-05-17 EP disclosed
US-9782336-B2 Moisturizer and cosmetic containing same AJINOMOTO CO., INC. (JP) 2017-10-10 US disclosed
EP-3192493-A1 MOISTURIZER AND COSMETIC CONTAINING SAME Ajinomoto Co., Inc. (JP) 2017-07-19 EP disclosed
US-20170181947-A1 MOISTURIZER AND COSMETIC CONTAINING SAME AJINOMOTO CO., INC. (JP) 2017-06-29 US disclosed
WO-1999065304-A1 COMPOSITIONS FOR PROTECTING PLANTS AGAINST OXIDATIVE STRESS MORELLE JEAN (FR) 1999-12-23 WO disclosed
EP-0784603-A2 RACEMISATION OF PRECURSORS TO LEVOBUPIVACAINE AND ANALOGUES THEREOF Chiroscience Limited (GB) 1997-07-23 EP disclosed
WO-1996011173-A2 RACEMISATION OF PRECURSORS TO LEVOBUPIVACAINE AND ANALOGUES THEREOF CHIROSCIENCE LIMITED (GB) 1996-04-18 WO disclosed
EP-0416282-A1 Microbiologically produced N-Acyl-L-proline-acylase, process for its production and its use Degussa Aktiengesellschaft (DE) 1991-03-13 EP disclosed
US-4837026-A Transdermal and systemic preparation and method THERAPEUTIC PATCH RESEARCH N.V. 1989-06-06 US disclosed
US-4797151-A Process for improving floral fertility DEMIL EDMOND A (FR) 1989-01-10 US disclosed
EP-0240554-A1 TRANSDERMAL AND SYSTEMIC PREPARATION AND METHOD RAJADHYAKSHA, Vithal J. (US) 1987-10-14 EP disclosed
WO-1987001935-A1 TRANSDERMAL AND SYSTEMIC PREPARATION AND METHOD RAJADHYAKSHA VITHAL J 1987-04-09 WO disclosed
CN-86101850-A N, the manufacture method and the purposes of N '-dialkyl group guanidine radicals dipeptides 1987-02-04 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170181947-A1 MOISTURIZER AND COSMETIC CONTAINING SAME PPT1, ACOX1, ALDH18A1 ACE 2920/4885REN 3408/4885LMNA 4844/4885
US-20250000948-A1 SOLID COMPOSITIONS COMPRISING A PEPTIDE OR A PROTEIN AND AN ACYLATED AMINO ACID NPPA, BCAT1, ANPEP ACE 684/4885REN 941/4885LMNA 3979/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.