Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APLNR | P35414 | 1/20 | 0.54 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA7 | P43166 | 2/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | CTSD | P07339 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27732646 | 0.87 | APLNR (0.54) | APLNRCA1CA7CA12CA14 | |
| SCHEMBL10535135 | 0.85 | APLNR (0.53) | APLNRMEN1KMT2AMAPTNPSR1 | |
| SCHEMBL3458796 | 0.84 | APLNR (0.54) | APLNRCA1CA7CA12CA14 | |
| SCHEMBL16906258 | 0.83 | APLNR (0.58) | APLNRCA1CA7CA12CA14 | |
| SCHEMBL10087239 | 0.82 | APLNR (0.53) | APLNRCA1CA7CA12CA14 | |
| SCHEMBL470134 | 0.82 | APLNR (0.53) | APLNRCA1CA7CA12CA14 | |
| SCHEMBL31626613 | 0.82 | APLNR (0.53) | APLNRCA1CA7CA12CA14 | |
| SCHEMBL14258516 | 0.82 | APLNR (0.53) | APLNRMEN1KMT2AGAAMAPK1 | |
| SCHEMBL20288786 | 0.82 | CA1 (0.43) | APLNRCA1CA7CA12CA14 | |
| SCHEMBL19136211 | 0.81 | APLNR (0.56) | APLNRCA1CA7CA12CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106164072-B | Monocyclic lactam organic compounds for the treatment of bacterial infections | 诺华股份有限公司 | 2019-10-01 | — | — | CN | disclosed |
| EP-1303528-A1 | ADENOSINE COMPOUND AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | Nikken Chemicals Company, Limited (JP) | 2003-04-23 | — | — | EP | disclosed |
| WO-2002004474-A1 | ADENOSINE COMPOUND AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | NIKKEN CHEMICALS CO. LTD. (JP) | 2002-01-17 | — | — | WO | disclosed |