Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APLNR | P35414 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 5/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | CA7 | P43166 | 2/20 | 0.36 |
| ▸ | CTSK | P43235 | 2/20 | 0.36 |
| ▸ | AKT1 | P31749 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 2/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7052487 | 0.82 | APLNR (0.54) | APLNRGAAMEN1KMT2AMAPK1 | |
| SCHEMBL3458796 | 0.82 | APLNR (0.54) | APLNRGAAMEN1KMT2AMAPK1 | |
| SCHEMBL10087239 | 0.81 | APLNR (0.53) | APLNRGAAMEN1KMT2AMAPK1 | |
| SCHEMBL14258516 | 0.81 | APLNR (0.53) | APLNRGAAMEN1KMT2AMAPK1 | |
| SCHEMBL31626613 | 0.81 | APLNR (0.53) | APLNRGAAMEN1KMT2AMAPK1 | |
| SCHEMBL15684322 | 0.79 | APLNR (0.51) | APLNRGAAMEN1KMT2AMAPK1 | |
| SCHEMBL19136211 | 0.79 | APLNR (0.56) | APLNRGAAMEN1KMT2AMAPK1 | |
| SCHEMBL284141 | 0.78 | APLNR (0.55) | APLNRGAAMEN1KMT2AMAPK1 | |
| SCHEMBL29139522 | 0.78 | APLNR (0.50) | APLNRGAAMEN1KMT2AMAPK1 | |
| SCHEMBL27732646 | 0.78 | APLNR (0.54) | APLNRGAAMEN1KMT2AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012031609-A1 | BIODEGRADABLE, WATER SOLUBLE AND PH RESPONSIVE POLY(ORGANO)PHOSPHAZENES | JOHANNES KEPLER UNIVERSITÄT LINZ (AT) | 2012-03-15 | — | — | WO | disclosed |