Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | DDX3X | O00571 | 1/20 | 0.43 |
| ▸ | KCNH3 | Q9ULD8 | 6/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7052508 | 1.00 | MAPT (0.45) | MAPTMEN1KMT2AALDH1A1MAPK1 | |
| SCHEMBL7054908 | 0.81 | MAPT (0.46) | MAPTMEN1KMT2AALDH1A1MAPK1 | |
| SCHEMBL7052510 | 0.75 | MAPT (0.41) | MAPTMEN1KMT2AALDH1A1MAPK1 | |
| SCHEMBL13641358 | 0.73 | NPY5R (0.56) | MAPTMEN1KMT2AALDH1A1MAPK1 | |
| SCHEMBL7057020 | 0.69 | KCNH3 (0.50) | MAPTMEN1KMT2AALDH1A1MAPK1 | |
| SCHEMBL10697527 | 0.68 | PDE4B (0.48) | MAPTMEN1KMT2AALDH1A1MAPK1 | |
| SCHEMBL7059634 | 0.68 | NEK2 (0.52) | MAPTMEN1KMT2AALDH1A1MAPK1 | |
| SCHEMBL633400 | 0.67 | MEN1 (0.77) | MAPTMEN1KMT2AALDH1A1MAPK1 | |
| SCHEMBL13861627 | 0.67 | NPY5R (0.61) | MAPTMEN1KMT2AALDH1A1MAPK1 | |
| SCHEMBL115405 | 0.66 | MAPT (0.57) | MAPTMEN1KMT2AALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6562833-B1 | Treating the fungi or the plants, seeds, material or the soil to be protected against fungal infection with a fungicidally effective amount of at least one 2-(N-phenylamino)pyrimidine | BASF AKTIENGESELLSCHAFT (DE) | 2003-05-13 | — | — | US | disclosed |
| EP-1085807-B1 | USE OF 2-(N-PHENYLAMINO)PYRIMIDINES AS FUNGICIDES, AND NOVEL 2-(N-PHENYLAMINO)PYRIMIDINES | BASF AG (DE) | 2003-05-07 | — | — | EP | disclosed |