Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NEK2 | P51955 | 1/20 | 0.52 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.50 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.50 |
| ▸ | CTSK | P43235 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.44 |
| ▸ | KCNH3 | Q9ULD8 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13641358 | 0.76 | NPY5R (0.56) | ALDH1A1HTTKCNH3NFKB1MEN1 | |
| SCHEMBL12233515 | 0.73 | ALDH1A1 (0.53) | NEK2ADORA2AADORA1CTSKALDH1A1 | |
| SCHEMBL7057020 | 0.73 | KCNH3 (0.50) | ALDH1A1HTTRECQLKCNH3NFKB1 | |
| SCHEMBL7054908 | 0.72 | MAPT (0.46) | ALDH1A1HTTKCNH3TDP1NFKB1 | |
| SCHEMBL6235242 | 0.72 | CTSK (0.76) | ADORA2AADORA1CTSKTDP1MEN1 | |
| SCHEMBL8961467 | 0.71 | TAAR1 (0.56) | ADORA2AADORA1CTSKALDH1A1HTT | |
| SCHEMBL24490436 | 0.70 | ABCG2 (0.59) | ADORA2AADORA1CTSKADORA2BTDP1 | |
| SCHEMBL24490452 | 0.70 | ABCG2 (0.59) | ADORA2AADORA1CTSKADORA2BTDP1 | |
| SCHEMBL7420353 | 0.70 | SMN1; SMN2 (0.64) | ALDH1A1NFKB1MEN1MAPTMAPK1 | |
| SCHEMBL633400 | 0.70 | MEN1 (0.77) | ALDH1A1RECQLKCNH3TDP1NFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6562833-B1 | Treating the fungi or the plants, seeds, material or the soil to be protected against fungal infection with a fungicidally effective amount of at least one 2-(N-phenylamino)pyrimidine | BASF AKTIENGESELLSCHAFT (DE) | 2003-05-13 | — | — | US | disclosed |
| EP-1085807-B1 | USE OF 2-(N-PHENYLAMINO)PYRIMIDINES AS FUNGICIDES, AND NOVEL 2-(N-PHENYLAMINO)PYRIMIDINES | BASF AG (DE) | 2003-05-07 | — | — | EP | disclosed |