SCHEMBL28096818

SCHEMBL28096818

O=COC(F)c1ccc(-c2ccccc2)cc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACP3 P15309 2/20 0.40
PTGS2 P35354 1/20 0.40
CHRNB2 P17787 1/20 0.38
CHRNA4 P43681 1/20 0.38
DRD1 P21728 2/20 0.36
CYP17A1 P05093 3/20 0.35
CYP3A4 P08684 2/20 0.35
ALDH1A1 P00352 2/20 0.35
MEN1 O00255 1/20 0.34
NR1I2 O75469 1/20 0.34
USP2 O75604 1/20 0.34
ABCB11 O95342 1/20 0.34
PLA2G1B P04054 1/20 0.34
TP53 P04637 1/20 0.34
PGR P06401 1/20 0.34
HSP90AA1 P07900 1/20 0.34
MAPT P10636 1/20 0.34
IDO1 P14902 1/20 0.34
HPGD P15428 1/20 0.34
MAOA P21397 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7052526 0.88 CYP2D6 (0.39) ALDH1A1MAPK1KMT2A
SCHEMBL29165673 0.74 ALDH1A1 (0.39) ACP3PTGS2CHRNB2CHRNA4CYP3A4
SCHEMBL6233892 0.73 PTGS2 (0.41) ACP3PTGS2CHRNB2CHRNA4CYP17A1
SCHEMBL4637121 0.69 ALDH1A1 (0.50) ACP3PTGS2CHRNB2CHRNA4CYP17A1
SCHEMBL2554928 0.69 ACP3 (0.47) ACP3PTGS2CHRNB2CHRNA4CYP3A4
SCHEMBL13368895 0.69 ACP3 (0.47) ACP3PTGS2CHRNB2CHRNA4CYP3A4
SCHEMBL332255 0.68 SRR (0.47) ACP3ALDH1A1MEN1KMT2ACYP1A2
SCHEMBL1515909 0.67 ACP3 (0.48) ACP3PTGS2CHRNB2CHRNA4CYP17A1
SCHEMBL7024449 0.67 DPP4 (0.41) CHRNB2CHRNA4ALDH1A1HTR2AMAPK1
Biphenyl SCHEMBL28018506 0.67 ALDH1A1 (0.53) CYP3A4ALDH1A1MEN1TP53MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105899521-A Method for preparing borylated aromatic hydrocarbons 陶氏益农公司 2016-08-24 CN disclosed