Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFKB1 | P19838 | 5/20 | 0.46 |
| ▸ | NFKB2 | Q00653 | 5/20 | 0.46 |
| ▸ | RELA | Q04206 | 5/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | PIM1 | P11309 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7052576 | 0.77 | MAPK1 (0.41) | NFKB1NFKB2RELAMAPK1 | |
| SCHEMBL13940276 | 0.76 | — | — | |
| SCHEMBL14209522 | 0.76 | — | — | |
| SCHEMBL852586 | 0.73 | NFKB1 (0.38) | NFKB1NFKB2RELA | |
| SCHEMBL968866 | 0.73 | NFKB1 (0.38) | NFKB1NFKB2RELA | |
| SCHEMBL968867 | 0.73 | NFKB1 (0.38) | NFKB1NFKB2RELA | |
| SCHEMBL9856833 | 0.73 | NFKB1 (0.49) | NFKB1NFKB2RELAMAPK1 | |
| SCHEMBL8578253 | 0.72 | NFKB1 (0.41) | NFKB1NFKB2RELA | |
| SCHEMBL3449840 | 0.71 | NFKB1 (0.37) | NFKB1NFKB2RELA | |
| SCHEMBL5634238 | 0.71 | NFKB1 (0.37) | NFKB1NFKB2RELA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5808112-A | Preparation of cis-4-O-protected-2-cyclopentenol derivatives | HOECHST MARION ROUSSEL INC. (US) | 1998-09-15 | — | — | US | disclosed |
| US-5728899-A | Preparation of cis-4-O-protected-2-cyclopentenol derivatives | HOECHST MARION ROUSSEL INC. (US) | 1998-03-17 | — | — | US | disclosed |
| EP-0817764-A1 | PREPARATION OF CIS-4-O-PROTECTED-2-CYCLOPENTENOL DERIVATIVES | HOECHST MARION ROUSSEL, INC. (US) | 1998-01-14 | — | — | EP | disclosed |
| WO-1996030320-A1 | PREPARATION OF CIS-4-O-PROTECTED-2-CYCLOPENTENOL DERIVATIVES | HOECHST MARION ROUSSEL, INC. (US) | 1996-10-03 | — | — | WO | disclosed |
| EP-0299907-B1 | Process for the preparation of diesters of symmetrical bicyclo[3.3.0]octanedionedicarboxylic acids | SCHERING AKTIENGESELLSCHAFT (DE) | 1992-03-04 | — | — | EP | disclosed |
| US-4912251-A | Process for manufacturing symmetrical diesters of bicyclo[3.3.0]-octanedione dicarboxylic acid | SCHERING AKTIENGESELLSCHAFT (DE) | 1990-03-27 | — | — | US | disclosed |
| WO-1989000555-A1 | PROCESS FOR MANUFACTURING SYMMETRICAL DIESTERS OF BICYCLO[3.3.0]-OCTANEDIONE DICARBOXYLIC ACID | SCHERING AKTIENGESELLSCHAFT BERLIN UND BERGKAMEN (DE) | 1989-01-26 | — | — | WO | disclosed |
| EP-0299907-A1 | Process for the preparation of diesters of symmetrical bicyclo[3.3.0]octanedionedicarboxylic acids | SCHERING AKTIENGESELLSCHAFT (DE) | 1989-01-18 | — | — | EP | disclosed |