Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 2/20 | 0.36 |
| ▸ | MAOB | P27338 | 2/20 | 0.36 |
| ▸ | KLKB1 | P03952 | 3/20 | 0.36 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.34 |
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.33 |
| ▸ | KLK1 | P06870 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | APEX1 | P27695 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL780340 | 0.78 | GPR35 (0.38) | MAOAMAOBGPR35CA12CA1 | |
| SCHEMBL874860 | 0.78 | GPR35 (0.38) | MAOAMAOBGPR35CA12CA1 | |
| SCHEMBL7054295 | 0.78 | TDP1 (0.41) | MAOAMAOBKLKB1GPR35MCL1 | |
| SCHEMBL2495583 | 0.76 | GPR35 (0.39) | GPR35CA12CA1CA2CA9 | |
| SCHEMBL29190982 | 0.73 | GPR35 (0.37) | MAOAMAOBGPR35CA12CA1 | |
| SCHEMBL16372656 | 0.71 | GPR35 (0.36) | GPR35CA12CA1CA2CA9 | |
| SCHEMBL17700941 | 0.69 | MCL1 (0.39) | GPR35CA12CA1CA2CA9 | |
| SCHEMBL4544341 | 0.67 | ALDH1A1 (0.39) | GPR35CA12CA9MCL1HSD17B10 | |
| SCHEMBL10693316 | 0.66 | POLB (0.37) | GPR35CA12CA1CA2CA9 | |
| SCHEMBL1607511 | 0.65 | RAB9A (0.42) | RAB9ASMN1; SMN2LMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003020877-A2 | STAINING AND SORTING GENOMES AND CHROMOSOMES USING SEQUENCE-SPECIFIC POLYAMIDES | PHARMACIA CORPORATION (US) | 2003-03-13 | — | — | WO | disclosed |