SCHEMBL7052836

SCHEMBL7052836

COC1(CN2CCN(S(=O)(=O)c3ccc4cc(Cl)ccc4c3)CC2=O)CCN(C(=O)OC(C)(C)C)CC1

nearest known ligand 0.40

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
STS P08842 2/20 0.40
F10 P00742 11/20 0.39
TGM2 P21980 3/20 0.39
MAPT P10636 1/20 0.38
GPR119 Q8TDV5 2/20 0.38
POLB P06746 1/20 0.38
F13A1 P00488 1/20 0.38
TGM1 P22735 1/20 0.38
F2 P00734 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7054303 0.89 STS (0.41) STSF10TGM2GPR119F13A1
SCHEMBL5741231 0.89 F10 (0.40) STSF10TGM2MAPTGPR119
SCHEMBL5741347 0.89 STS (0.40) STSF10TGM2MAPTGPR119
SCHEMBL7051249 0.87 STS (0.40) STSF10TGM2GPR119F13A1
SCHEMBL7115070 0.86 STS (0.38) STSF10TGM2GPR119F13A1
SCHEMBL7115064 0.86 LMNA (0.39) STSF10TGM2F13A1TGM1
SCHEMBL5741924 0.84 MAPT (0.42) STSF10TGM2MAPTPOLB
SCHEMBL6895114 0.83 STS (0.46) STSF10MAPTGPR119
SCHEMBL6887446 0.83 GPR119 (0.47) STSF10TGM2GPR119F13A1
Hydrochloric Acid SCHEMBL7053310 0.82 F10 (0.41) F10MAPTPOLBF2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6680312-B2 FOR THERAPY OF CARDIAC INFARCTION, CEREBRAL THROMBOSIS; INHIBIT ACTIVATED COAGULATION FACTOR X (FXA) TO SHOW ANTI-COAGULANT ACTIVITY TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 2004-01-20 US disclosed
US-20020193382-A1 Sulfonamide derivatives, their production and use TAKEDA PHARMACEUTICAL COMPANY, LIMITED (JP) 2002-12-19 US disclosed
US-6403595-B1 ANTICOAGULANTS TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 2002-06-11 US disclosed
EP-1054005-A1 SULFONAMIDE DERIVATIVES, PROCESS FOR PRODUCING THE SAME AND UTILIZATION THEREOF Takeda Chemical Industries, Ltd. (JP) 2000-11-22 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020193382-A1 Sulfonamide derivatives, their production and use F12, F11, F2 STS 13/4885F10 5/4885TGM2 2701/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.