Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MIF | P14174 | 1/20 | 0.61 |
| ▸ | RAB9A | P51151 | 7/20 | 0.60 |
| ▸ | NPC1 | O15118 | 5/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.60 |
| ▸ | RECQL | P46063 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 6/20 | 0.58 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.56 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.56 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7052868 | 1.00 | MIF (0.61) | MIFRAB9ANPC1SMN1; SMN2RECQL | |
| SCHEMBL13916291 | 1.00 | MIF (0.61) | MIFRAB9ANPC1SMN1; SMN2RECQL | |
| SCHEMBL7716956 | 0.88 | RAB9A (0.59) | MIFRAB9ANPC1SMN1; SMN2RECQL | |
| SCHEMBL7919338 | 0.88 | LMNA (0.63) | MIFRAB9ANPC1SMN1; SMN2MAPT | |
| SCHEMBL6444624 | 0.83 | MAPT (0.72) | MIFRAB9ANPC1SMN1; SMN2RECQL | |
| SCHEMBL3550155 | 0.81 | HDAC3 (0.65) | RAB9ANPC1SMN1; SMN2MAPTHDAC3 | |
| SCHEMBL27076797 | 0.81 | HDAC3 (0.65) | RAB9ANPC1SMN1; SMN2MAPTHDAC3 | |
| SCHEMBL3550150 | 0.81 | HDAC3 (0.65) | RAB9ANPC1SMN1; SMN2MAPTHDAC3 | |
| SCHEMBL3266677 | 0.80 | MAPT (0.76) | MIFRAB9ANPC1SMN1; SMN2RECQL | |
| SCHEMBL12979794 | 0.80 | MAPT (0.76) | MIFRAB9ANPC1SMN1; SMN2RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0979820-B1 | 2-Phenylpyridine derivatives and production method thereof | SUMIKA FINE CHEMICALS CO LTD (JP) | 2003-05-07 | — | — | EP | claimed |
| US-6147218-A | 2-phenylpyridine derivative and production method thereof | SUMIKA FINE CHEMICALS CO., LTD. (JP) | 2000-11-14 | — | — | US | claimed |
| EP-0979820-A1 | 2-Phenylpyridine derivatives and production method thereof | SUMIKA FINE CHEMICALS Co., Ltd. (JP) | 2000-02-16 | — | — | EP | claimed |
| EP-2522367-B1 | Oligomer-protease inhibitor conjugates | NEKTAR THERAPEUTICS (US) | 2016-01-20 | — | — | EP | disclosed |
| US-9107956-B2 | Oligomer-protease inhibitor conjugates | NEKTAR THERAPEUTICS (US) | 2015-08-18 | — | — | US | disclosed |
| US-9095620-B2 | Reagents | NEKTAR THERAPEUTICS (US) | 2015-08-04 | — | — | US | disclosed |
| EP-2262538-B1 | OLIGOMER-AMINO ACID CONJUGATE | NEKTAR THERAPEUTICS (US) | 2014-12-10 | — | — | EP | disclosed |
| US-20140045770-A1 | OLIGOMER-PROTEASE INHIBITOR CONJUGATES | NEKTAR THERAPEUTICS (US) | 2014-02-13 | — | — | US | disclosed |
| WO-2012170792-A1 | ATAZANAVIR METABOLITE DERIVATIVES | CONCERT PHARMACEUTICALS, INC. (US) | 2012-12-13 | — | — | WO | disclosed |
| EP-2522367-A1 | Oligomer-protease inhibitor conjugates | Nektar Therapeutics (US) | 2012-11-14 | — | — | EP | disclosed |
| US-20110269677-A1 | Oligomer-Protease Inhibitor Conjugates | NEKTAR THERAPEUTICS (US) | 2011-11-03 | — | — | US | disclosed |
| US-20020022730-A1 | Method for producing hydrazine derivative | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2002-02-21 | — | — | US | disclosed |
| US-6268503-B1 | REACTING 2-(4-BROMOMETHYLPHENYL)PYRIDINE SALT OR 2-(4-DIBROMOMETHYLPHENYL)PYRIDINE WITH HEXAMETHYLENETETRAMINE AND WATER TO PROVIDE 4-(PYRIDIN-2-YL)BENZALDEHYDE | SUMIKA FINE CHEMICALS CO., LTD. (JP) | 2001-07-31 | — | — | US | disclosed |
| US-6268503-B1 | REACTING 2-(4-BROMOMETHYLPHENYL)PYRIDINE SALT OR 2-(4-DIBROMOMETHYLPHENYL)PYRIDINE WITH HEXAMETHYLENETETRAMINE AND WATER TO PROVIDE 4-(PYRIDIN-2-YL)BENZALDEHYDE | SUMIKA FINE CHEMICALS CO., LTD. (JP) | 2001-07-31 | — | — | US | disclosed |
| US-6242608-B1 | REACTING 4-(PYRIDIN-2-YL)BENZALDEHYDE WITH HYDRAZINE TO FORM 4-(PYRIDIN-2-YL)BENZALDEHYDE HYDRAZONE; CHEMICAL INTERMEDIATE TO AN ANTI-HIV DRUG | SUMIKA FINE CHEMICALS CO., LTD. (JP) | 2001-06-05 | — | — | US | disclosed |
| US-6242608-B1 | REACTING 4-(PYRIDIN-2-YL)BENZALDEHYDE WITH HYDRAZINE TO FORM 4-(PYRIDIN-2-YL)BENZALDEHYDE HYDRAZONE; CHEMICAL INTERMEDIATE TO AN ANTI-HIV DRUG | SUMIKA FINE CHEMICALS CO., LTD. (JP) | 2001-06-05 | — | — | US | disclosed |
| US-6147218-A | 2-phenylpyridine derivative and production method thereof | SUMIKA FINE CHEMICALS CO., LTD. (JP) | 2000-11-14 | — | — | US | disclosed |
| US-6147218-A | 2-phenylpyridine derivative and production method thereof | SUMIKA FINE CHEMICALS CO., LTD. (JP) | 2000-11-14 | — | — | US | disclosed |
| EP-0979820-A1 | 2-Phenylpyridine derivatives and production method thereof | SUMIKA FINE CHEMICALS Co., Ltd. (JP) | 2000-02-16 | — | — | EP | disclosed |
| EP-0979820-A1 | 2-Phenylpyridine derivatives and production method thereof | SUMIKA FINE CHEMICALS Co., Ltd. (JP) | 2000-02-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020022730-A1 | Method for producing hydrazine derivative | H1-2, H1-0, HRH2 | MIF 4377/4885RAB9A 1851/4885NPC1 2765/4885 |
| US-20140045770-A1 | OLIGOMER-PROTEASE INHIBITOR CONJUGATES | DNPEP, ADAM17, SERPINB1 | MIF 602/4885RAB9A 2708/4885NPC1 368/4885 |
| US-20110269677-A1 | Oligomer-Protease Inhibitor Conjugates | ADAM17, DNPEP, SERPINB1 | MIF 569/4885RAB9A 3122/4885NPC1 571/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.