Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | DRD4 | P21917 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
| ▸ | HTR7 | P34969 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
| ▸ | PGR | P06401 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8856830 | 0.83 | PNMT (0.38) | PNMTNPC1RAB9ADRD2DRD4 | |
| Hydrochloric Acid SCHEMBL27461639 | 0.76 | PNMT (0.34) | PNMTNPC1RAB9ADRD2DRD4 | |
| SCHEMBL7052931 | 0.73 | PNMT (0.39) | PNMTNPC1RAB9AHTR7HTR2B | |
| SCHEMBL524602 | 0.71 | PNMT (0.63) | PNMTNPC1RAB9ADRD2DRD4 | |
| SCHEMBL30103334 | 0.71 | PNMT (0.63) | PNMTNPC1RAB9ADRD2DRD4 | |
| SCHEMBL7057184 | 0.70 | PNMT (0.36) | PNMTNPC1RAB9AHTR7HTR2B | |
| Hydrochloric Acid SCHEMBL17845923 | 0.69 | PNMT (0.46) | PNMTNPC1RAB9ADRD2DRD4 | |
| SCHEMBL2877998 | 0.69 | PNMT (0.61) | PNMTNPC1RAB9ADRD2DRD4 | |
| SCHEMBL8468716 | 0.69 | PNMT (0.49) | PNMTNPC1RAB9ADRD2DRD4 | |
| Hydrochloric Acid SCHEMBL540483 | 0.68 | PNMT (0.52) | PNMTNPC1RAB9ADRD2DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8536286-B2 | Composite catalyst for production of polyethylene | CHINA PETROLEUM & CHEMICAL CORPORATION (CN) | 2013-09-17 | — | — | US | disclosed |
| US-20100152397-A1 | COMPOSITE CATALYST FOR PRODUCTION OF POLYETHYLENE | ZHEJIANG UNIVERSITY (CN) | 2010-06-17 | — | — | US | disclosed |