Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 9/20 | 0.45 |
| ▸ | DRD3 | P35462 | 9/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | HTR1A | P08908 | 2/20 | 0.41 |
| ▸ | HTR2A | P28223 | 2/20 | 0.41 |
| ▸ | HTR2C | P28335 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7058078 | 0.89 | DRD2 (0.56) | DRD2DRD3ADRA1AHTR1AHTR2A | |
| SCHEMBL7057687 | 0.87 | CCR3 (0.50) | DRD2DRD3ADRA1ACCR3 | |
| SCHEMBL7053088 | 0.87 | DRD3 (0.49) | DRD2DRD3ADRA1ATP53HTR2A | |
| SCHEMBL7055659 | 0.82 | DRD2 (0.50) | DRD2DRD3ADRA1ACCR3 | |
| SCHEMBL7119593 | 0.81 | CCR3 (0.55) | DRD2DRD3ADRA1ACCR3 | |
| SCHEMBL7060979 | 0.80 | DRD2 (0.52) | DRD2DRD3ADRA1ACCR3 | |
| SCHEMBL7057584 | 0.79 | DRD3 (0.69) | DRD2DRD3ADRA1A | |
| SCHEMBL7054406 | 0.77 | DRD3 (0.57) | DRD2DRD3ADRA1AHTR1AHTR2A | |
| SCHEMBL7055557 | 0.76 | DRD3 (0.58) | DRD2DRD3ADRA1AHTR1AHTR2A | |
| SCHEMBL7052427 | 0.76 | DRD2 (0.48) | DRD2DRD3ADRA1AHTR1AHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003028725-A1 | 4-(1-PIPERIDINY)-BUTYLCARBOXAMIDE AS D3 DOPAMINE RECEPTOR SUBTYPE SELECTIVE LIGANDS | Richter Gedeon Vegyészeti Gyár Rt. (HU) | 2003-04-10 | — | — | WO | disclosed |