Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 2/20 | 0.53 |
| ▸ | HTR2C | P28335 | 1/20 | 0.53 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.53 |
| ▸ | HTR6 | P50406 | 2/20 | 0.49 |
| ▸ | MET | P08581 | 2/20 | 0.47 |
| ▸ | ADRB1 | P08588 | 5/20 | 0.46 |
| ▸ | NCF1 | P14598 | 2/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | DRD3 | P35462 | 1/20 | 0.46 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.46 |
| ▸ | HTR3B | O95264 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | HTR1D | P28221 | 1/20 | 0.46 |
| ▸ | HTR1B | P28222 | 1/20 | 0.46 |
| ▸ | HTR7 | P34969 | 1/20 | 0.46 |
| ▸ | MTOR | P42345 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5363544 | 0.98 | HTR2A (0.51) | HTR2AHTR2CSLC6A4HTR6MET | |
| SCHEMBL17109415 | 0.85 | KMT2A (0.54) | TSHRHSD17B10ALDH1A1LMNAPOLB | |
| SCHEMBL6391081 | 0.83 | KMT2A (0.57) | NCF1TSHRHSD17B10ALDH1A1LMNA | |
| SCHEMBL5363405 | 0.75 | HTR2A (0.67) | HTR2AHTR2CSLC6A4HTR6ADRB1 | |
| SCHEMBL21224877 | 0.75 | ALDH1A1 (0.46) | HTR6ALDH1A1LMNAPOLBPKM | |
| SCHEMBL4888354 | 0.74 | KMT2A (0.56) | HTR2AHTR2CSLC6A4HTR6ADRB1 | |
| Hydrochloric Acid SCHEMBL5251427 | 0.73 | KMT2A (0.55) | HTR2AHTR2CSLC6A4HTR6ADRB1 | |
| SCHEMBL9220891 | 0.73 | POLB (0.40) | HTR3EHTR3BCYP1A2CYP2D6TSHR | |
| SCHEMBL15834279 | 0.70 | ADRB1 (0.75) | HTR2ASLC6A4HTR6ADRB1NCF1 | |
| SCHEMBL3289568 | 0.69 | HTR2A (0.50) | HTR2AHTR2CSLC6A4HTR6ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030181446-A1 | Novel N-acylated heterocycles | RECORDATI S.A. | 2003-09-25 | — | — | US | disclosed |
| US-20030162777-A1 | Novel N-acylated heterocycles | RECORDATI S.A. | 2003-08-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030162777-A1 | Novel N-acylated heterocycles | HTR1A, HTR1D, HTR1E | HTR2A 8/4885HTR2C 6/4885SLC6A4 90/4885 |
| US-20030181446-A1 | Novel N-acylated heterocycles | HTR1A, HTR1E, HTR2C | HTR2A 8/4885HTR2C 3/4885SLC6A4 62/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.