Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 5/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.33 |
| ▸ | CNR1 | P21554 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.33 |
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.33 |
| ▸ | USP8 | P40818 | 1/20 | 0.33 |
| ▸ | USP7 | Q93009 | 1/20 | 0.33 |
| ▸ | USP47 | Q96K76 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7053365 | 0.75 | KDM4E (0.44) | ALDH1A1MEN1KMT2AKDM4EMAPT | |
| SCHEMBL27467198 | 0.74 | ALDH1A1 (0.40) | ALDH1A1MEN1KMT2ACNR1KDM4E | |
| SCHEMBL27163963 | 0.74 | TRPA1 (0.40) | ALDH1A1HPGDELANESLC6A2SLC6A4 | |
| SCHEMBL30784894 | 0.74 | TRPA1 (0.40) | ALDH1A1HPGDELANESLC6A2SLC6A4 | |
| SCHEMBL9373813 | 0.73 | ALDH1A1 (0.42) | ALDH1A1HPGDSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL27669229 | 0.71 | ALDH1A1 (0.40) | ALDH1A1HPGDELANESLC6A2SLC6A4 | |
| SCHEMBL460268 | 0.70 | SLC6A2 (0.53) | ALDH1A1SLC6A2SLC6A4SLC6A3KMT2A | |
| SCHEMBL10567133 | 0.70 | LMNA (0.46) | ALDH1A1MEN1KMT2AKDM4EMAPT | |
| SCHEMBL126343 | 0.68 | PDE10A (0.51) | ALDH1A1HPGDMEN1KMT2AKDM4E | |
| SCHEMBL30832623 | 0.68 | PDE10A (0.51) | ALDH1A1HPGDMEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003026664-A1 | 2-PHENYLAMINO-4- (5-PYRAZOLYLAMINO) -PYRAMIDINE DERIVATIVES AS KINASE INHIBITORS, IN PARTICULAR, SRC KINASE INHIBITORS | BAYER CORPORATION (US) | 2003-04-03 | — | — | WO | disclosed |