SCHEMBL7053371

SCHEMBL7053371

O=C(O)c1ccccc1-c1ccc(O)c([N+](=O)[O-])c1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.51
KCNMA1 Q12791 1/20 0.49
ACMSD Q8TDX5 3/20 0.49
MCL1 Q07820 3/20 0.49
CRHBP P24387 1/20 0.47
CRHR2 Q13324 1/20 0.47
EIF4E P06730 3/20 0.46
TSHR P16473 2/20 0.46
MAPK1 P28482 2/20 0.46
ALDH1A1 P00352 2/20 0.46
SMN1; SMN2 Q16637 2/20 0.46
TP53 P04637 1/20 0.46
HPGD P15428 1/20 0.46
GPR35 Q9HC97 1/20 0.46
DHFR P00374 1/20 0.45
HNF4A P41235 1/20 0.45
ALOX15 P16050 1/20 0.45
HSD17B10 Q99714 1/20 0.45
L3MBTL1 Q9Y468 1/20 0.45
ABCB1 P08183 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1897366 0.94 KCNMA1 (0.53) MAPTKCNMA1ACMSDMCL1CRHBP
SCHEMBL7168661 0.94 KCNMA1 (0.53) MAPTKCNMA1ACMSDMCL1CRHBP
SCHEMBL27585698 0.88 CASP6 (0.51) KCNMA1CRHBPCRHR2EIF4ETSHR
SCHEMBL19025730 0.87 ALDH1A1 (0.53) MAPTCRHBPCRHR2EIF4ETSHR
SCHEMBL29789033 0.87 ALDH1A1 (0.53) MAPTCRHBPCRHR2EIF4ETSHR
SCHEMBL5216747 0.84 TSHR (0.55) MAPTMCL1EIF4ETSHRMAPK1
SCHEMBL6261436 0.84 SLC25A1 (0.55) MAPTEIF4EALDH1A1DHFR
SCHEMBL8473662 0.84 SLC25A1 (0.55) MAPTEIF4EALDH1A1DHFR
SCHEMBL16538208 0.84 EIF4E (0.51) MAPTACMSDEIF4ETSHRALDH1A1
SCHEMBL2533703 0.81 TSHR (0.55) MCL1EIF4ETSHRSMN1; SMN2HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6569504-B1 Dimers of LC-like compounds in which the monomers are linked to each other through a high birefringence moiety (dimerization linker) DISPLAYTECH, INC. 2003-05-27 US disclosed
EP-1307426-A1 AMINO DIPHENYL ETHERS AND AMIDO DIPHENYL ETHERS Bayer Aktiengesellschaft (DE) 2003-05-07 EP disclosed
WO-2002012169-A1 AMINO DIPHENYL ETHERS AND AMIDO DIPHENYL ETHERS BAYER AKTIENGESELLSCHAFT (DE) 2002-02-14 WO disclosed
US-6139771-A USEFUL IN ELECTOOPTICAL AND NON-LINEAR OPTICAL APPLICATIONS DISPLAYTECH, INC. (US) 2000-10-31 US disclosed