SCHEMBL705339

SCHEMBL705339

CCC(c1ccccc1)(c1ccccc1)c1ccccc1O[SiH3]

nearest known ligand 0.38

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
KCNN4 O15554 1/20 0.33
KIF11 P52732 6/20 0.33
SIGMAR1 Q99720 1/20 0.33
MAPK1 P28482 1/20 0.32
CHRM2 P08172 1/20 0.32
CHRM1 P11229 1/20 0.32
CHRM3 P20309 1/20 0.32
KCNH2 Q12809 2/20 0.32
RIPK1 Q13546 1/20 0.32
TAAR1 Q96RJ0 1/20 0.31
ALDH1A1 P00352 1/20 0.31
ALOX15 P16050 1/20 0.31
HTR2A P28223 1/20 0.30
HTR2C P28335 1/20 0.30
ADRA1A P35348 1/20 0.30
OPRK1 P41145 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL702494 0.76 ESR1 (0.41) KCNN4MAPK1TAAR1ALDH1A1ALOX15
SCHEMBL1971090 0.73 KCNN4 (0.48) KCNN4KIF11SIGMAR1MAPK1TAAR1
SCHEMBL985016 0.72 ALDH1A1 (0.48) KCNN4KIF11SIGMAR1KCNH2ALDH1A1
SCHEMBL27656875 0.72 KCNN4 (0.44) KCNN4KIF11KCNH2ALDH1A1OPRK1
SCHEMBL20686352 0.72 KIF11 (0.39) KCNN4KIF11KCNH2TAAR1ALDH1A1
SCHEMBL10938605 0.72 KCNN4 (0.36) KCNN4KIF11SIGMAR1MAPK1CHRM2
SCHEMBL6555560 0.72 KCNN4 (0.36) KCNN4KIF11CHRM2CHRM1CHRM3
SCHEMBL13062957 0.72 KCNN4 (0.52) KCNN4KIF11MAPK1CHRM2CHRM1
SCHEMBL705017 0.70 ALDH1A1 (0.44) ALDH1A1ALOX15
SCHEMBL30639004 0.68 ALDH1A1 (0.48) KCNN4KIF11SIGMAR1KCNH2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9546237-B2 Stabilization of polymers that contain a hydrolyzable functionality BRIDGESTONE CORPORATION (JP) 2017-01-17 US disclosed
US-20130331520-A1 STABILIZATION OF POLYMERS THAT CONTAIN A HYDROLYZABLE FUNCTIONALITY BRIDGESTONE CORPORATION (JP) 2013-12-12 US disclosed
US-8124239-B2 Silica film forming material, silica film and method of manufacturing the same, multilayer wiring structure and method of manufacturing the same, and semiconductor device and method of manufacturing the same FUJITSU LIMITED (JP) 2012-02-28 US disclosed
US-20100155121-A1 SILICA FILM FORMING MATERIAL, SILICA FILM AND METHOD OF MANUFACTURING THE SAME, MULTILAYER WIRING STRUCTURE AND METHOD OF MANUFACTURING THE SAME, AND SEMICONDUCTOR DEVICE AND METHOD OF MANUFACTURING THE SAME FUJITSU LIMITED (JP) 2010-06-24 US disclosed
US-7659357-B2 Precursor organosilicon polymer of 1,2-Bis(dimethylethoxysilyl)ethane, 1,4-bis(dimethylethoxysilyl)benzene, tetraethoxysilane, methyltriethoxysilane, phenyltriethoxysilane; dielectric (DE) films having etching/chemical/moisture resistance; adhesion; low DE constant; minimal wiring delay; high speed FUJITSU LIMITED (JP) 2010-02-09 US disclosed
US-20070026689-A1 Silica film forming material, silica film and method of manufacturing the same, multilayer wiring structure and method of manufacturing the same, and semiconductor device and method of manufacturing the same FUJITSU LIMITED (JP) 2007-02-01 US disclosed