SCHEMBL705017

SCHEMBL705017

CC(C)(C)c1ccccc1O[SiH3]

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.44
TDP1 Q9NUW8 4/20 0.44
TSHR P16473 1/20 0.44
ATM Q13315 1/20 0.44
CYP1A2 P05177 1/20 0.43
CYP2D6 P10635 1/20 0.43
CYP2C19 P33261 1/20 0.43
HSD17B10 Q99714 1/20 0.43
KDM4E B2RXH2 3/20 0.41
GAA P10253 2/20 0.41
RXRA P19793 1/20 0.41
RXRB P28702 1/20 0.41
RXRG P48443 1/20 0.41
CA2 P00918 1/20 0.41
MAPT P10636 2/20 0.40
NISCH Q9Y2I1 1/20 0.40
BCHE P06276 1/20 0.39
NPSR1 Q6W5P4 3/20 0.38
HTT P42858 2/20 0.38
NAMPT P43490 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL706108 0.83 ALDH1A1 (0.39) ALDH1A1TDP1TSHRATMCYP1A2
SCHEMBL28426083 0.80 CA2 (0.41) ALDH1A1TDP1TSHRATMCYP1A2
SCHEMBL30500977 0.80 ALDH1A1 (0.48) ALDH1A1TDP1TSHRATMCYP1A2
SCHEMBL127278 0.80 ALDH1A1 (0.48) ALDH1A1TDP1TSHRATMCYP1A2
SCHEMBL702494 0.79 ESR1 (0.41) ALDH1A1TDP1ATMCYP1A2CYP2D6
SCHEMBL142899 0.78 CA2 (0.57) ALDH1A1TDP1TSHRATMCYP1A2
SCHEMBL6933536 0.78 ALDH1A1 (0.46) ALDH1A1TDP1TSHRATMCYP1A2
SCHEMBL29771456 0.78 CA2 (0.57) ALDH1A1TDP1TSHRATMCYP1A2
SCHEMBL711563 0.77 CA2 (0.35) ALDH1A1TDP1TSHRATMCYP1A2
SCHEMBL1053934 0.76 PPARG (0.41) ALDH1A1TDP1GAARXRARXRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109641482-B Preparation of cis-1, 4-polydienes having multiple silane functional groups prepared by in situ hydrosilylation of polymer glues 株式会社普利司通 2021-11-05 CN disclosed
US-8124239-B2 Silica film forming material, silica film and method of manufacturing the same, multilayer wiring structure and method of manufacturing the same, and semiconductor device and method of manufacturing the same FUJITSU LIMITED (JP) 2012-02-28 US disclosed
US-20100155121-A1 SILICA FILM FORMING MATERIAL, SILICA FILM AND METHOD OF MANUFACTURING THE SAME, MULTILAYER WIRING STRUCTURE AND METHOD OF MANUFACTURING THE SAME, AND SEMICONDUCTOR DEVICE AND METHOD OF MANUFACTURING THE SAME FUJITSU LIMITED (JP) 2010-06-24 US disclosed
US-7659357-B2 Precursor organosilicon polymer of 1,2-Bis(dimethylethoxysilyl)ethane, 1,4-bis(dimethylethoxysilyl)benzene, tetraethoxysilane, methyltriethoxysilane, phenyltriethoxysilane; dielectric (DE) films having etching/chemical/moisture resistance; adhesion; low DE constant; minimal wiring delay; high speed FUJITSU LIMITED (JP) 2010-02-09 US disclosed
CN-101360513-A Biodegradable and thermosensitive poly(organophosphazene) hydrogel, preparation method thereof and use thereof KOREA INST SCI & TECH (KR) 2009-02-04 CN disclosed
US-20070026689-A1 Silica film forming material, silica film and method of manufacturing the same, multilayer wiring structure and method of manufacturing the same, and semiconductor device and method of manufacturing the same FUJITSU LIMITED (JP) 2007-02-01 US disclosed
EP-1586578-A2 Method of removing allyl series protecting group using novel ruthenium complex and method of synthesizing allyl ethers NAGOYA UNIVERSITY (JP) 2005-10-19 EP disclosed
US-20050203317-A1 Method of removing allyl series protecting group using novel ruthenium complex and method of synthesizing allyl ethers NAGOYA UNIVERSITY, A NATIONAL UNIV. CORP. OF JP (JP) 2005-09-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050203317-A1 Method of removing allyl series protecting group using novel ruthenium complex and method of synthesizing allyl ethers AP2M1, AP3M1, AP2A2 ALDH1A1 2918/4885TDP1 4727/4885TSHR 1496/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.