SCHEMBL290872

SCHEMBL290872

CC(C)(C)C(=O)OCCc1ccccc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 1/20 0.53
TDP1 Q9NUW8 2/20 0.52
ESR1 P03372 1/20 0.51
ESR2 Q92731 1/20 0.51
NPC1 O15118 2/20 0.50
RAB9A P51151 2/20 0.50
L3MBTL1 Q9Y468 2/20 0.50
ALDH1A1 P00352 2/20 0.50
AKR1B10 O60218 2/20 0.50
AKR1B1 P15121 2/20 0.50
TP53 P04637 1/20 0.50
GLA P06280 1/20 0.50
CYP3A4 P08684 1/20 0.50
HPGD P15428 1/20 0.50
TSHR P16473 1/20 0.50
MAPK1 P28482 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.50
HIF1A Q16665 1/20 0.50
HSD17B10 Q99714 1/20 0.50
POLB P06746 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8663566 0.89 LMNA (0.62) TDP1NPC1RAB9AALDH1A1AKR1B10
SCHEMBL3935097 0.88 LMNA (0.56) TDP1NPC1RAB9ASMN1; SMN2POLB
Acetic Acid Phenyl Ester SCHEMBL28249394 0.88 NPC1 (0.49) HCAR2TDP1ESR1ESR2NPC1
SCHEMBL26358186 0.86 HCAR2 (0.50) HCAR2TDP1ESR1ESR2NPC1
SCHEMBL19105206 0.86 HCAR2 (0.50) HCAR2TDP1ESR1ESR2NPC1
SCHEMBL8392743 0.86 HCAR2 (0.50) HCAR2TDP1ESR1ESR2NPC1
SCHEMBL5326607 0.86 HCAR2 (0.50) HCAR2TDP1ESR1ESR2NPC1
SCHEMBL12128696 0.86 HCAR2 (0.50) HCAR2TDP1ESR1ESR2NPC1
SCHEMBL1606962 0.84 RIPK1 (0.49) HCAR2TDP1ESR1ESR2NPC1
SCHEMBL11009163 0.84 L3MBTL1 (0.49) HCAR2TDP1ESR1ESR2NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 337 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025125201-A1 AQUEOUS DISPERSION COMPRISING POLYMER PARTICLES FOR IMPROVING THE RESISTANCE OF WATERBORNE COATINGS BASF SE (DE) 2025-06-19 WO claimed
US-20250129312-A1 CONSUMER PRODUCT COMPOSITIONS WITH PERFUME ENCAPSULATES PROCTER & GAMBLE (US) 2025-04-24 US claimed
US-12209232-B2 Consumer product compositions with perfume encapsulates THE PROCTER & GAMBLE COMPANY (US) 2025-01-28 US claimed
US-20230340375-A1 CONSUMER PRODUCT COMPOSITIONS WITH PERFUME ENCAPSULATES PROCTER & GAMBLE (US) 2023-10-26 US claimed
US-11732222-B2 Consumer product compositions with perfume encapsulates THE PROCTER & GAMBLE COMPANY (US) 2023-08-22 US claimed
EP-2072083-B1 Utilisation of 2.4'-dimethyl-propiophenon as an aroma SYMRISE AG (DE) 2012-02-15 EP claimed
US-20090162308-A1 USE OF 2,4'-DIMETHYLPROPIOPHENONE AS A FRAGRANCE SUBSTANCE SYMRISE GMBH & CO. KG (DE) 2009-06-25 US claimed
US-20060166857-A1 4,8-Dimethyl-7-nonen-2-one and 4,8-dimethylnonan-2-one used as perfumes SYMRISE GMBH & CO. KG (DE) 2006-07-27 US claimed
US-6844302-B1 Encapsulated flavor and fragrance INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 2005-01-18 US claimed
US-6780835-B2 DEODORANT FOR TREATING TEXTILES INCORPORATING SPANDEX QUEST INTERNATIONAL B.V. (NL) 2004-08-24 US claimed
EP-1029032-B1 LAUNDRY TREATMENT PRODUCTS FOR SPANDEX CONTAINING FABRICS UNILEVER PLC (GB) 2004-03-03 EP claimed
US-6660288-B1 Particularly for mosquitoes; tricyclodecenyl allyl ether perfume (Fleuroxene\"); hydrophobicity such that the common logarithm of the octanol-water partition coefficient, log P, of the perfume ingredient is in the range 1.0 to 6.0 QUEST INTERNATIONAL B.V. (NL) 2003-12-09 US claimed
EP-0883675-B1 DETERGENT COMPOSITIONS CONTAINING ENDURING PERFUME PROCTER & GAMBLE (US) 2003-09-03 EP claimed
EP-1119250-B1 INSECT REPELLENTS QUEST INT (NL) 2002-11-06 EP claimed
EP-0885279-B1 FABRIC SOFTENER COMPOSITION WITH IMPROVED ENVIRONMENTAL IMPACT PROCTER & GAMBLE (US) 2002-09-11 EP claimed
EP-1119250-A1 INSECT REPELLENTS QUEST INTERNATIONAL NEDERLAND BV (NL) 2001-08-01 EP claimed
WO-2000019822-A1 INSECT REPELLENTS QUEST INTERNATIONAL B.V. (NL) 2000-04-13 WO claimed
US-12589377-B2 Encapsulated composition comprising core-shell microcapsules and process for its preparation GIVAUDAN SA (CH) 2026-03-31 US disclosed
WO-1999018926-A1 PERFUME COMPOSITIONS QUEST INTERNATIONAL B.V. (NL) 1999-04-22 WO disclosed
WO-1999019452-A1 LAUNDRY TREATMENT PRODUCTS FOR SPANDEX® CONTAINING FABRICS UNILEVER PLC (GB) 1999-04-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090162308-A1 USE OF 2,4'-DIMETHYLPROPIOPHENONE AS A FRAGRANCE SUBSTANCE CYP1B1, CYP4A22, ROS1 HCAR2 1953/4885TDP1 3882/4885ESR1 1354/4885
US-12589377-B2 Encapsulated composition comprising core-shell microcapsules and process for its preparation CUTA, EXOC1, EXOSC10 HCAR2 4455/4885TDP1 1746/4885ESR1 4304/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.