SCHEMBL7203782

SCHEMBL7203782

CC1=Cc2ccccc2C1[Si](C)(C)[Ti]

nearest known ligand 0.30

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 1/20 0.30
CYP11B1 P15538 1/20 0.30
CYP11B2 P19099 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7055976 0.86 CYP11B1 (0.33) CYP19A1CYP11B1CYP11B2
SCHEMBL7053946 0.84 CYP19A1 (0.32) CYP19A1CYP11B1CYP11B2
SCHEMBL61361 0.84 CYP19A1 (0.32) CYP19A1CYP11B1CYP11B2
SCHEMBL29844183 0.84 CYP19A1 (0.32) CYP19A1CYP11B1CYP11B2
SCHEMBL4612462 0.82 CYP19A1 (0.31) CYP19A1CYP11B1CYP11B2
SCHEMBL1822867 0.82 CYP19A1 (0.31) CYP19A1CYP11B1CYP11B2
Lithium SCHEMBL29644507 0.82 CYP19A1 (0.31) CYP19A1CYP11B1CYP11B2
SCHEMBL7055450 0.82 CYP11B1 (0.33) CYP19A1CYP11B1CYP11B2
Hydrochloric Acid SCHEMBL2970565 0.81 CYP11B1 (0.33) CYP19A1CYP11B1CYP11B2
Hydrochloric Acid SCHEMBL7196460 0.81 CYP19A1 (0.30) CYP19A1CYP11B1CYP11B2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20030171207-A1 Metallocene and constrained geometry catalyst systems employing agglomerated metal oxide/clay support-activator and method of their preparation SHIH KENG-YU (US) 2003-09-11 US disclosed
US-20020169262-A1 Functionalized catalyst supports and supported catalyst systems THE DOW CHEMICAL COMPANY 2002-11-14 US disclosed
EP-1242478-A1 METALLOCENE AND CONSTRAINED GEOMETRY CATALYST SYSTEMS EMPLOYING AGGLOMERATED METAL OXIDE/CLAY SUPPORT-ACTIVATOR AND METHOD OF THEIR PREPARATION W. R. Grace & Co.-Conn (US) 2002-09-25 EP disclosed
WO-2001032721-A1 METALLOCENE AND CONSTRAINED GEOMETRY CATALYST SYSTEMS EMPLOYING AGGLOMERATED METAL OXIDE/CLAY SUPPORT-ACTIVATOR AND METHOD OF THEIR PREPARATION W. R. GRACE & CO.-CONN. (US) 2001-05-10 WO disclosed
WO-1997049738-A1 INCORPORATION OF FUNCTIONALIZED COMONOMERS IN POLYOLEFINS THE DOW CHEMICAL COMPANY (US) 1997-12-31 WO disclosed