Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 9/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CPA1 | P15085 | 3/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7056737 | 0.81 | ALDH1A1 (0.34) | ARPOLBCPA1TP53HTT | |
| SCHEMBL7054295 | 0.75 | TDP1 (0.41) | ARTDP1CYP2C9MEN1POLB | |
| SCHEMBL2830141 | 0.75 | TDP1 (0.41) | ARTDP1CYP2C9MEN1POLB | |
| SCHEMBL1662655 | 0.74 | AR (0.51) | ARTDP1CYP2C9MEN1POLB | |
| Hydrochloric Acid SCHEMBL6151019 | 0.72 | AR (0.50) | ARTDP1CYP2C9MEN1POLB | |
| SCHEMBL1666475 | 0.72 | TDP1 (0.40) | ARTDP1CYP2C9MEN1POLB | |
| SCHEMBL11779027 | 0.67 | CASP6 (0.41) | TDP1MEN1KMT2ATP53HCAR3 | |
| SCHEMBL5174989 | 0.66 | TDP1 (0.46) | ARTDP1CYP2C9MEN1POLB | |
| SCHEMBL2783116 | 0.66 | CYP2C9 (0.54) | TDP1CYP2C9MEN1POLBKMT2A | |
| SCHEMBL3674837 | 0.66 | TDP1 (0.46) | ARTDP1CYP2C9MEN1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003020877-A2 | STAINING AND SORTING GENOMES AND CHROMOSOMES USING SEQUENCE-SPECIFIC POLYAMIDES | PHARMACIA CORPORATION (US) | 2003-03-13 | — | — | WO | disclosed |