SCHEMBL7054636

SCHEMBL7054636

CC1=Cc2c(-c3ccccc3)cccc2C1[Si](C)(Cl)c1ccccc1

nearest known ligand 0.30

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PDCD1 Q15116 1/20 0.30
CD274 Q9NZQ7 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7048706 0.87 PDCD1 (0.31) PDCD1CD274
SCHEMBL1825035 0.87 PDCD1 (0.33) PDCD1CD274
SCHEMBL7051179 0.87 PDCD1 (0.33) PDCD1CD274
SCHEMBL7048688 0.87 PDCD1 (0.34) PDCD1CD274
SCHEMBL5837068 0.86 PDCD1 (0.32) PDCD1CD274
SCHEMBL7050759 0.85 PDCD1 (0.35) PDCD1CD274
SCHEMBL7050672 0.84 ENPP3 (0.33)
SCHEMBL5837366 0.84 PDCD1 (0.33) PDCD1CD274
SCHEMBL7053161 0.84 PDCD1 (0.34) PDCD1CD274
SCHEMBL29366427 0.84 PDCD1 (0.34) PDCD1CD274

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0985674-B1 ORGANIC COMPOUNDS CONTAINING SILICON OR GERMANIUM, TRANSITION METAL COMPLEXES, CATALYST FOR ALPHA-OLEFIN POLYMERIZATION, AND PROCESSES FOR PRODUCING ALPHA-OLEFIN POLYMERS MITSUBISHI CHEM CORP (JP) 2003-04-23 EP disclosed
US-6255515-B1 COORDINATION POLYMERIZATION CATALYSTS MITSUBISHI CHEMICAL CORPORATION (JP) 2001-07-03 US disclosed
EP-0985674-A1 ORGANIC COMPOUNDS CONTAINING SILICON OR GERMANIUM, TRANSITION METAL COMPLEXES, CATALYST FOR $g(a)-OLEFIN POLYMERIZATION, AND PROCESSES FOR PRODUCING $g(a)-OLEFIN POLYMERS MITSUBISHI CHEMICAL CORPORATION (JP) 2000-03-15 EP disclosed