⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20524986 | 0.82 | CYP2A6 (0.32) | — | |
| SCHEMBL64917 | 0.78 | CYP1A2 (0.40) | — | |
| SCHEMBL3237917 | 0.78 | CA1 (0.30) | — | |
| SCHEMBL8533924 | 0.78 | — | — | |
| SCHEMBL5227738 | 0.78 | CYP1A2 (0.40) | — | |
| SCHEMBL328780 | 0.75 | LTA4H (0.42) | — | |
| SCHEMBL2500175 | 0.74 | — | — | |
| SCHEMBL637304 | 0.74 | HTT (0.31) | — | |
| SCHEMBL16593572 | 0.74 | — | — | |
| SCHEMBL5545821 | 0.74 | HTT (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9551029-B2 | Methods and kits using extended rhodamine dyes | APPLIED BIOSYSTEMS, LLC (US) | 2017-01-24 | — | — | US | disclosed |
| US-20160122813-A1 | Methods And Kits Using Extended Rhodamine Dyes | THE PERKIN-ELMER CORPORATION | 2016-05-05 | — | — | US | disclosed |
| US-9309561-B2 | Methods and kits using extended rhodamine dyes | APPLIED BIOSYSTEMS, LLC (US) | 2016-04-12 | — | — | US | disclosed |
| US-20140171336-A1 | Methods and Kits Using Extended Rhodamine Dyes | Life Technologies Corporation (US) | 2014-06-19 | — | — | US | disclosed |
| US-8628975-B2 | Methods and kits using extended rhodamine dyes | APPLIED BIOSYSTEMS, LLC (US) | 2014-01-14 | — | — | US | disclosed |
| US-20120135885-A1 | Methods and Kits Using Extended Rhodamine Dyes | Life Technologies Corporation (US) | 2012-05-31 | — | — | US | disclosed |
| US-8124746-B2 | Methods and kits using extended rhodamine dyes | APPLIED BIOSYSTEMS, LLC (US) | 2012-02-28 | — | — | US | disclosed |
| US-20110053282-A1 | Methods and Kits Using Extended Rhodamine Dyes | Life Technologies Corporation (US) | 2011-03-03 | — | — | US | disclosed |
| US-7776568-B2 | Rhodamine dye compounds for patterns with DNA sequences for kits | APPLIED BIOSYSTEMS, LLC (US) | 2010-08-17 | — | — | US | disclosed |
| US-20050027130-A1 | Rhodamine dye compounds for patterns with DNA sequences for kits | APPLERA CORPORATION (US) | 2005-02-03 | — | — | US | disclosed |
| US-6781001-B2 | EXTENDED RHODAMINE DYE COMPOUND SUITABLE FOR THE CREATING OF SETS OF SPACTRALLY RESOLVABLE FLUORESCENT LABELS PARTICLULARLY USEFUL FOR FLUORESCENCE BASED DNA SEQUENCING SYSTEM | APPLERA CORPORATION | 2004-08-24 | — | — | US | disclosed |
| EP-1416017-A1 | Fluorescent nucleosides, nucleotides or polynucleotides containing a rhodamine dye | Applera Corporation (US) | 2004-05-06 | — | — | EP | disclosed |
| EP-1181335-B1 | EXTENDED RHODAMINE COMPOUNDS USEFUL AS FLUORESCENT LABELS | APPLERA CORP (US) | 2004-01-28 | — | — | EP | disclosed |
| EP-1181335-A1 | EXTENDED RHODAMINE COMPOUNDS USEFUL AS FLUORESCENT LABELS | PE Corporation (NY) (US) | 2002-02-27 | — | — | EP | disclosed |
| US-20010007905-A1 | Extended rhodamine dye compound suitable for the creating of sets of spactrally resolvable fluorescent labels particlularly useful for fluorescence based DNA sequencing system | THE PERKIN-ELMER CORPORATION | 2001-07-12 | — | — | US | disclosed |
| US-6248884-B1 | PARTICULARLY WELL SUITED FOR USE IN AUTOMATED FLUORESCENCE-BASED DNA SEQUENCING SYSTEMS USING AN EXCITATION LIGHT SOURCE HAVING A WAVELENGTH GREATER THAN ABOUT 630 NM, E.G., A HELIUM-NEON GAS LASER OR A SOLID STATE DIODE LASER. | THE PERKIN-ELMER CORPORATION | 2001-06-19 | — | — | US | disclosed |
| WO-2000075236-A1 | EXTENDED RHODAMINE COMPOUNDS USEFUL AS FLUORESCENT LABELS | PE CORPORATION (NY) (US) | 2000-12-14 | — | — | WO | disclosed |