SCHEMBL703111

SCHEMBL703111

[SiH3]OCCC(c1ccccc1)(c1ccccc1)c1ccccc1

nearest known ligand 0.48

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 15/20 0.48
KCNH2 Q12809 3/20 0.41
CYP11B1 P15538 1/20 0.38
CYP11B2 P19099 1/20 0.38
CYP2D6 P10635 2/20 0.37
CYP3A4 P08684 1/20 0.37
CYP2C9 P11712 1/20 0.37
CYP2C19 P33261 1/20 0.37
CHRM4 P08173 1/20 0.35
CHRM5 P08912 1/20 0.35
CHRM3 P20309 1/20 0.35
LMNA P02545 1/20 0.35
CHRM2 P08172 1/20 0.35
HTR1A P08908 1/20 0.35
CHRM1 P11229 1/20 0.35
OPRM1 P35372 1/20 0.35
MAPK1 P28482 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3482027 0.89 KIF11 (0.57) KIF11KCNH2CYP2D6CYP3A4CYP2C9
SCHEMBL705749 0.87 KIF11 (0.55) KIF11KCNH2CYP11B1CYP11B2CYP2D6
SCHEMBL23701213 0.78 TSHR (0.41) KIF11MAPK1
SCHEMBL23701252 0.78 TSHR (0.41) KIF11MAPK1
SCHEMBL3867726 0.78 KIF11 (0.46) KIF11KCNH2CYP2D6CYP3A4CYP2C9
SCHEMBL2326286 0.77 KIF11 (0.48) KIF11KCNH2CYP11B1CYP11B2CYP2D6
SCHEMBL1149158 0.77 KIF11 (0.64) KIF11KCNH2CYP11B1CYP11B2CYP2D6
SCHEMBL20483662 0.77 PTPN1 (0.39) KCNH2CYP2D6CYP3A4MAPK1
SCHEMBL238217 0.76 KIF11 (0.41) KIF11KCNH2CYP11B1CYP11B2CYP2C9
SCHEMBL10604505 0.75 KIF11 (0.49) KIF11LMNAMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7129311-B2 Additives to prevent degradation of alkyl-hydrogen siloxanes ARCH SPECIALTY CHEMICALS, INC. (US) 2006-10-31 US claimed
US-20060159861-A1 Additives to prevent degradation of alkyl-hydrogen siloxanes ARCH SPECIALTY CHEMICALS, INC. (US) 2006-07-20 US claimed
EP-1573086-A2 ADDITIVES TO PREVENT DEGRADATION OF ALKYL-HYDROGEN SILOXANES Arch Specialty Chemicals, Inc. (US) 2005-09-14 EP claimed
US-20040127070-A1 Additives to prevent degradation of alkyl-hydrogen siloxanes ARCH SPECIALTY CHEMICALS, INC. 2004-07-01 US claimed
WO-2004027110-A2 ADDITIVES TO PREVENT DEGRADATION OF ALKYL-HYDROGEN SILOXANES ARCH SPECIALTY CHEMICALS, INC. (US) 2004-04-01 WO claimed
US-12312494-B2 Resin composition, method for producing same, and multi-liquid curable resin composition KANEKA CORPORATION (JP) 2025-05-27 US disclosed
CN-116410664-B Insulating coating composition suitable for electrophoretic coating, preparation method of insulating coating composition, coating, preparation method of coating and battery pack 比亚迪股份有限公司 2024-10-11 CN disclosed
CN-118647671-A Resin composition, cured product, sheet-like laminate, resin sheet, printed wiring board, and semiconductor device 味之素株式会社 2024-09-13 CN disclosed
CN-115003759-B Resin composition, method for producing same, and multicomponent curable resin composition 株式会社钟化 2023-12-01 CN disclosed
WO-2023149521-A1 RESIN COMPOSITION, CURED PRODUCT, SHEET-LIKE LAYERED MATERIAL, RESIN SHEET, PRINTED WIRING BOARD, AND SEMICONDUCTOR DEVICE 味の素株式会社 2023-08-10 WO disclosed
CN-116410664-A Insulating coating composition suitable for electrophoretic coating, preparation method of insulating coating composition, coating, preparation method of coating and battery pack 比亚迪股份有限公司 2023-07-11 CN disclosed
US-20220340777-A1 RESIN COMPOSITION, METHOD FOR PRODUCING SAME, AND MULTI-LIQUID CURABLE RESIN COMPOSITION KANEKA CORPORATION (JP) 2022-10-27 US disclosed
US-7129311-B2 Additives to prevent degradation of alkyl-hydrogen siloxanes ARCH SPECIALTY CHEMICALS, INC. (US) 2006-10-31 US disclosed
US-20060159861-A1 Additives to prevent degradation of alkyl-hydrogen siloxanes ARCH SPECIALTY CHEMICALS, INC. (US) 2006-07-20 US disclosed
EP-1573086-A2 ADDITIVES TO PREVENT DEGRADATION OF ALKYL-HYDROGEN SILOXANES Arch Specialty Chemicals, Inc. (US) 2005-09-14 EP disclosed
US-20040127070-A1 Additives to prevent degradation of alkyl-hydrogen siloxanes ARCH SPECIALTY CHEMICALS, INC. 2004-07-01 US disclosed
WO-2004027110-A2 ADDITIVES TO PREVENT DEGRADATION OF ALKYL-HYDROGEN SILOXANES ARCH SPECIALTY CHEMICALS, INC. (US) 2004-04-01 WO disclosed
US-6344579-B1 REACTION OF FLUOROSILICON COMPOUND WITH REACTION OF SILICON WITH HYDROXY, ALKOXY OR ARYLOXY GROUP WITH DIFLUORODIAMINO COMPOUND MITSUI CHEMICALS, INC. (JP) 2002-02-05 US disclosed
EP-1138633-A1 PROCESS FOR PRODUCING FLUORINATED SILICON COMPOUND Mitsui Chemicals, Inc. (JP) 2001-10-04 EP disclosed
EP-0193643-A2 Curable resin composition KABUSHIKI KAISHA TOSHIBA (JP) 1986-09-10 EP disclosed