SCHEMBL705750

SCHEMBL705750

CCC(c1ccccc1)C(O[SiH3])(c1ccccc1)c1ccccc1

nearest known ligand 0.38

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.38
CYP1A2 P05177 1/20 0.36
CYP3A4 P08684 1/20 0.36
CYP2C9 P11712 1/20 0.36
TSHR P16473 1/20 0.36
CYP2C19 P33261 1/20 0.36
HKDC1 Q2TB90 1/20 0.35
MEN1 O00255 7/20 0.35
KMT2A Q03164 7/20 0.35
POLB P06746 1/20 0.35
ATM Q13315 1/20 0.33
KCNN4 O15554 1/20 0.33
NPC1 O15118 1/20 0.33
SIGMAR1 Q99720 1/20 0.33
MIF P14174 1/20 0.33
MAPK1 P28482 1/20 0.32
TRPA1 O75762 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28491863 0.85 LMNA (0.41) LMNACYP1A2CYP3A4CYP2C9TSHR
SCHEMBL1314414 0.81 KIF11 (0.39) LMNACYP3A4CYP2C19KMT2AKCNN4
SCHEMBL4452175 0.81 LMNA (0.37) LMNACYP1A2CYP3A4CYP2C9TSHR
SCHEMBL3868242 0.81 TSHR (0.33) LMNATSHR
SCHEMBL4530142 0.81 LMNA (0.37) LMNACYP1A2CYP3A4CYP2C9TSHR
SCHEMBL4452178 0.78 LMNA (0.39) LMNACYP1A2CYP3A4CYP2C9TSHR
SCHEMBL532851 0.78 LMNA (0.39) LMNACYP1A2CYP3A4CYP2C9TSHR
SCHEMBL705584 0.78 LMNA (0.35) LMNAMEN1KMT2APOLBATM
SCHEMBL11126896 0.78 POLB (0.38) LMNACYP1A2CYP3A4CYP2C9TSHR
SCHEMBL706206 0.78 LMNA (0.41) LMNACYP1A2CYP3A4CYP2C9TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115155113-B Structure for organic silicon defoamer and synthesis method thereof 佛山市南海大田化学有限公司 2023-09-29 CN claimed
CN-115105868-B Organic silicon defoamer and preparation method thereof 佛山市南海大田化学有限公司 2023-07-18 CN claimed
CN-115105868-A Organic silicon defoaming agent and preparation method thereof 佛山市南海大田化学有限公司 2022-09-27 CN claimed
US-7129311-B2 Additives to prevent degradation of alkyl-hydrogen siloxanes ARCH SPECIALTY CHEMICALS, INC. (US) 2006-10-31 US claimed
US-20060159861-A1 Additives to prevent degradation of alkyl-hydrogen siloxanes ARCH SPECIALTY CHEMICALS, INC. (US) 2006-07-20 US claimed
EP-1573086-A2 ADDITIVES TO PREVENT DEGRADATION OF ALKYL-HYDROGEN SILOXANES Arch Specialty Chemicals, Inc. (US) 2005-09-14 EP claimed
US-20040127070-A1 Additives to prevent degradation of alkyl-hydrogen siloxanes ARCH SPECIALTY CHEMICALS, INC. 2004-07-01 US claimed
WO-2004027110-A2 ADDITIVES TO PREVENT DEGRADATION OF ALKYL-HYDROGEN SILOXANES ARCH SPECIALTY CHEMICALS, INC. (US) 2004-04-01 WO claimed
CN-115155113-B Structure for organic silicon defoamer and synthesis method thereof 佛山市南海大田化学有限公司 2023-09-29 CN disclosed
CN-115105868-B Organic silicon defoamer and preparation method thereof 佛山市南海大田化学有限公司 2023-07-18 CN disclosed
CN-115105868-A Organic silicon defoaming agent and preparation method thereof 佛山市南海大田化学有限公司 2022-09-27 CN disclosed
CN-111448224-A Urea-bonded tetrafunctional (meth) acrylate compound and composition containing same 捷恩智株式会社 2020-07-24 CN disclosed
WO-2019194108-A1 UREA-BINDING TETRAFUNCTIONAL (METH)ACRYLATE COMPOUND AND COMPOSITION CONTAINING SAME JNC株式会社 2019-10-10 WO disclosed
WO-2019194107-A1 RESIN COMPOSITION JNC株式会社 2019-10-10 WO disclosed
EP-0682086-A2 Resin composition and a method of curing the same KANSAI PAINT CO., LTD. (JP) 1995-11-15 EP disclosed
EP-0681003-A2 Resin composition and a method of curing the same KANSAI PAINT CO., LTD. (JP) 1995-11-08 EP disclosed
US-5389727-A Low temperature curing, weatherproofing KANSAI PAINT COMPANY, LIMITED (JP) 1995-02-14 US disclosed
US-5284919-A Low temperature curing, waterproofing, acid resistance KANSAI PAINT COMPANY, LIMITED (JP) 1994-02-08 US disclosed
US-5026793-A Containing hydroxy, epoxy, and silane compounds with chelate compound containing aluminum, titanium, or zironium KANSAI PAINT COMPANY LIMITED (JP) 1991-06-25 US disclosed
EP-0358238-A2 Resin compositions and a method of curing the same KANSAI PAINT CO., LTD. (JP) 1990-03-14 EP disclosed