Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 13/20 | 0.71 |
| ▸ | DRD2 | P14416 | 11/20 | 0.71 |
| ▸ | HTR2A | P28223 | 4/20 | 0.71 |
| ▸ | HTR1A | P08908 | 3/20 | 0.71 |
| ▸ | HTR2C | P28335 | 3/20 | 0.71 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.57 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.57 |
| ▸ | DRD4 | P21917 | 4/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.52 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | PLD2 | O14939 | 1/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.49 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.49 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.49 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.49 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7119593 | 0.84 | CCR3 (0.55) | DRD3DRD2ADRA1A | |
| SCHEMBL7057584 | 0.84 | DRD3 (0.69) | DRD3DRD2SLC6A2SLC6A4DRD4 | |
| Hydrochloric Acid SCHEMBL7056135 | 0.83 | DRD4 (0.59) | DRD3DRD2HTR2AHTR1AHTR2C | |
| SCHEMBL4525593 | 0.83 | DRD2 (1.00) | DRD3DRD2HTR2AHTR1AHTR2C | |
| Hydrochloric Acid SCHEMBL7058141 | 0.81 | DRD2 (0.53) | DRD3DRD2HTR2AHTR1AHTR2C | |
| SCHEMBL7053098 | 0.80 | RAB9A (0.53) | DRD3DRD2HTR2AHTR1AHTR2C | |
| SCHEMBL7054406 | 0.80 | DRD3 (0.57) | DRD3DRD2HTR2AHTR1AHTR2C | |
| SCHEMBL7055659 | 0.80 | DRD2 (0.50) | DRD3DRD2ADRA1A | |
| SCHEMBL7060979 | 0.80 | DRD2 (0.52) | DRD3DRD2DRD4ADRA1A | |
| SCHEMBL7052435 | 0.78 | DRD2 (0.48) | DRD3DRD2HTR2AHTR1AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003028725-A1 | 4-(1-PIPERIDINY)-BUTYLCARBOXAMIDE AS D3 DOPAMINE RECEPTOR SUBTYPE SELECTIVE LIGANDS | Richter Gedeon Vegyészeti Gyár Rt. (HU) | 2003-04-10 | — | — | WO | disclosed |