Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 5/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.47 |
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
| ▸ | ADK | P55263 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | TDP2 | O95551 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | GALK1 | P51570 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10300820 | 0.75 | SLC6A4 (0.53) | SLC6A4SLC6A2SLC6A3KDM1AEPHX1 | |
| SCHEMBL2464189 | 0.75 | SLC6A4 (0.53) | SLC6A4SLC6A2SLC6A3KDM1AEPHX1 | |
| SCHEMBL5852684 | 0.75 | SLC6A4 (0.53) | SLC6A4SLC6A2SLC6A3KDM1AEPHX1 | |
| SCHEMBL30360438 | 0.75 | SLC6A4 (0.46) | SLC6A4SLC6A2SLC6A3KDM1AEPHX1 | |
| Methyl Alcohol SCHEMBL8766877 | 0.74 | SLC6A4 (0.49) | SLC6A4SLC6A2SLC6A3KDM1AEPHX1 | |
| SCHEMBL3073148 | 0.73 | SLC6A4 (0.45) | SLC6A4SLC6A2SLC6A3KDM1AEPHX1 | |
| SCHEMBL25338654 | 0.73 | MTNR1A (0.50) | SLC6A4SLC6A2SLC6A3KDM1AEPHX1 | |
| SCHEMBL5699413 | 0.72 | SLC6A4 (0.50) | SLC6A4SLC6A2SLC6A3KDM1AEPHX1 | |
| SCHEMBL13116598 | 0.70 | ADRA2A (0.41) | — | |
| SCHEMBL29137625 | 0.69 | SLC6A4 (0.44) | SLC6A4SLC6A2SLC6A3KDM1AEPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6608215-B2 | Photochromic ophthalmic or sun protection lenses, glass paneling | VISION-EASE LENS, INC. | 2003-08-19 | — | — | US | disclosed |
| US-20030092918-A1 | Oxygen-containing heterocyclic fused naphthopyrans | VISION-EASE LENS, INC. | 2003-05-15 | — | — | US | disclosed |
| WO-2003025638-A1 | OXYGEN-CONTAINING HETEROCYCLIC FUSED NAPHTHOPYRANS | VISION-EASE LENS, INC. (US) | 2003-03-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030092918-A1 | Oxygen-containing heterocyclic fused naphthopyrans | NQO1, NFE2L2, NDUFV2 | SLC6A4 4503/4885SLC6A2 4347/4885SLC6A3 4296/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.