Trifluoromethanesulfonic Acid

Trifluoromethanesulfonic Acid

SCHEMBL7058003

COc1ccc([S+]2CCCCC2)cc1.O=S(=O)([O-])C(F)(F)F

nearest known ligand 0.41

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KCNH2 Q12809 1/20 0.41
HTT P42858 1/20 0.41
PKM P14618 3/20 0.40
GAA P10253 3/20 0.38
HSD11B1 P28845 1/20 0.38
NPC1 O15118 1/20 0.37
PKLR P30613 1/20 0.37
RAB9A P51151 1/20 0.37
ALDH1A1 P00352 3/20 0.37
PTGS1 P23219 2/20 0.36
PTGS2 P35354 2/20 0.36
KDM4E B2RXH2 1/20 0.36
ACHE P22303 2/20 0.36
KMT2A Q03164 1/20 0.35
MMP2 P08253 2/20 0.35
CA1 P00915 1/20 0.35
CA2 P00918 1/20 0.35
MMP1 P03956 1/20 0.35
MMP9 P14780 1/20 0.35
MMP8 P22894 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoromethanesulfonic Acid SCHEMBL5353660 0.98 KCNH2 (0.42) KCNH2HTTPKMGAAHSD11B1
SCHEMBL7055556 0.86 HTT (0.38) KCNH2HTTPKMGAAHSD11B1
SCHEMBL5350460 0.85 GAA (0.37) KCNH2HTTPKMGAAHSD11B1
SCHEMBL5357438 0.84 GAA (0.36) KCNH2HTTPKMGAAHSD11B1
Trifluoromethanesulfonic Acid SCHEMBL36223 0.83 GPR3 (0.38) KCNH2HTTPKMGAAALDH1A1
SCHEMBL4569613 0.82 CA1 (0.48) HTTGAANPC1RAB9AALDH1A1
Trifluoromethanesulfonic Acid SCHEMBL36289 0.81 GPR3 (0.39) KCNH2HTTPKMGAAALDH1A1
Trifluoromethanesulfonic Acid SCHEMBL3150414 0.81 CA12 (0.46) KCNH2HTTNPC1RAB9AALDH1A1
Trifluoromethanesulfonic Acid SCHEMBL36792 0.80 KCNH2 (0.37) KCNH2CA1CA2
Trifluoromethanesulfonic Acid SCHEMBL36325 0.80 GPR3 (0.42) KCNH2HTTACHECA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20030134227-A1 Cyclic sulfonium and sulfoxonium photoacid generators and photoresists comprising same SHIPLEY COMPANY, LLC 2003-07-17 US disclosed
EP-1308781-A2 Cyclic sulfonium and sulfoxonium photoacid generators and photoresists containing them Shipley Co. L.L.C. (US) 2003-05-07 EP disclosed