Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | AOC3 | Q16853 | 5/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11078122 | 0.77 | LMNA (0.35) | TSHRLMNACYP2D6 | |
| SCHEMBL11078121 | 0.77 | LMNA (0.35) | TSHRLMNACYP2D6 | |
| SCHEMBL28619769 | 0.75 | RIPK1 (0.46) | RIPK1LMNAKDM4EL3MBTL1AOC3 | |
| SCHEMBL11301651 | 0.73 | CYP1A2 (0.36) | TSHRLMNAKDM4EL3MBTL1CYP1A2 | |
| SCHEMBL11301653 | 0.73 | CYP1A2 (0.36) | TSHRLMNAKDM4EL3MBTL1CYP1A2 | |
| SCHEMBL5185803 | 0.72 | RIPK1 (0.64) | RIPK1LMNAKDM4EL3MBTL1AOC3 | |
| SCHEMBL3081755 | 0.72 | RIPK1 (0.64) | RIPK1LMNAKDM4EL3MBTL1AOC3 | |
| SCHEMBL634044 | 0.72 | KDM4E (0.52) | RIPK1LMNAKDM4EL3MBTL1AOC3 | |
| SCHEMBL22444520 | 0.72 | RIPK1 (0.50) | RIPK1LMNAKDM4EL3MBTL1AOC3 | |
| SCHEMBL11378052 | 0.72 | RIPK1 (0.50) | RIPK1TSHRLMNAKDM4EL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1305280-A2 | PROCESS FOR MAKING 3-HYDROXYALKANENITRILES AND HYDROXYAMINOALKANES | E. I. du Pont de Nemours and Company (US) | 2003-05-02 | — | — | EP | disclosed |
| US-6384263-B1 | Process for making 3-hydroxyalkanelnitriles and conversion of the 3-hydroxyalkanelnitrile to an hydroxyaminoalkane | E. I. DU PONT DE NEMOURS AND COMPANY | 2002-05-07 | — | — | US | disclosed |
| US-20020022737-A1 | Process for making 3-hydroxyalkanelnitriles and conversion of the 3-hydroxyalkanelnitrile to an hydroxyaminoalkane | INV NYLON CHEMICALS AMERICAS, LLC | 2002-02-21 | — | — | US | disclosed |
| WO-2002012173-A2 | PROCESS FOR MAKING 3-HYDROXYALKANENITRILES AND HYDROXYAMINOALKANES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2002-02-14 | — | — | WO | disclosed |