Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CCR5 | P51681 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | MIF | P14174 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.30 |
| ▸ | HTR2A | P28223 | 2/20 | 0.30 |
| ▸ | HRH1 | P35367 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11078122 | 1.00 | LMNA (0.35) | LMNACCR5SMN1; SMN2MIFTAAR1 | |
| SCHEMBL11301651 | 0.86 | CYP1A2 (0.36) | LMNASMN1; SMN2CYP2D6TSHRSIGMAR1 | |
| SCHEMBL11301653 | 0.86 | CYP1A2 (0.36) | LMNASMN1; SMN2CYP2D6TSHRSIGMAR1 | |
| SCHEMBL6987943 | 0.83 | LMNA (0.37) | LMNACCR5SMN1; SMN2MIFTAAR1 | |
| SCHEMBL6987947 | 0.83 | LMNA (0.37) | LMNACCR5SMN1; SMN2MIFTAAR1 | |
| SCHEMBL5852964 | 0.80 | LMNA (0.39) | LMNACCR5MIFTAAR1CYP2D6 | |
| SCHEMBL5852961 | 0.80 | LMNA (0.39) | LMNACCR5MIFTAAR1CYP2D6 | |
| SCHEMBL7384257 | 0.78 | LMNA (0.41) | LMNACCR5MIFTAAR1CYP2D6 | |
| SCHEMBL7058065 | 0.77 | RIPK1 (0.43) | LMNACYP2D6TSHR | |
| SCHEMBL4908362 | 0.74 | LMNA (0.41) | LMNACCR5SMN1; SMN2MIFTAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4472319-A | Preparation of unsaturated nitriles using a surfactant | PHILLIPS PETROLEUM COMPANY (US) | 1984-09-18 | — | — | US | disclosed |