Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.50 |
| ▸ | NPC1 | O15118 | 6/20 | 0.50 |
| ▸ | GAA | P10253 | 4/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.50 |
| ▸ | IDO1 | P14902 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.42 |
| ▸ | RAB9A | P51151 | 5/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.38 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7139471 | 0.79 | DCUN1D1 (0.49) | KDM4ENPC1GAAHSD17B10IDO1 | |
| SCHEMBL19029698 | 0.78 | IDO1 (0.44) | KDM4ENPC1GAAHSD17B10IDO1 | |
| SCHEMBL18770391 | 0.78 | ADORA3 (0.42) | KDM4EALDH1A1L3MBTL1SMN1; SMN2RAB9A | |
| SCHEMBL11960986 | 0.76 | PDGFRB (0.47) | KDM4EHSD17B10ALDH1A1MEN1KMT2A | |
| SCHEMBL1208150 | 0.75 | ALDH1A1 (0.48) | KDM4ENPC1GAAHSD17B10IDO1 | |
| SCHEMBL16481851 | 0.75 | HSP90AA1 (0.50) | KDM4EGAAHSD17B10ALDH1A1SMN1; SMN2 | |
| SCHEMBL16481863 | 0.74 | HSD11B1 (0.47) | HSD17B10TDP1AR | |
| SCHEMBL11626478 | 0.74 | IDO1 (0.41) | KDM4ENPC1GAAHSD17B10IDO1 | |
| SCHEMBL14300518 | 0.73 | CYP1A2 (0.46) | KDM4ENPC1ALDH1A1SMN1; SMN2RAB9A | |
| SCHEMBL1008901 | 0.72 | MEN1 (0.46) | KDM4ENPC1GAAALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1307431-A2 | EFFICIENT LIGAND-MEDIATED ULLMANN COUPLING OF ANILINES AND AZOLES | Bristol-Myers Squibb Pharma Company (US) | 2003-05-07 | — | — | EP | disclosed |
| WO-2002008199-A2 | EFFICIENT LIGAND-MEDIATED ULLMANN COUPLING OF ANILINES AND AZOLES | BRISTOL-MYERS SQUIBB PHARMA COMPANY (US) | 2002-01-31 | — | — | WO | disclosed |
| WO-1989004845-A1 | NITROGEN-CONTAINING ESTERS OF CARBOXY-CONTAINING INTERPOLYMERS | THE LUBRIZOL CORPORATION (US) | 1989-06-01 | — | — | WO | disclosed |