Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 2/20 | 0.51 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 2/20 | 0.44 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.41 |
| ▸ | AR | P10275 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2688515 | 0.79 | MAOB (0.53) | ALOX5ALDH1A1MAPTHPGDSMN1; SMN2 | |
| SCHEMBL4556548 | 0.76 | ALOX5 (0.42) | ALOX5ALDH1A1MAPTKDM4EHPGD | |
| SCHEMBL28216130 | 0.76 | ALOX5 (0.46) | ALOX5ALDH1A1MAPTKDM4EHPGD | |
| SCHEMBL4549091 | 0.75 | MAOB (0.43) | ALOX5ALDH1A1HPGDSMN1; SMN2NPC1 | |
| SCHEMBL30488585 | 0.73 | ALOX5 (0.55) | ALOX5ALDH1A1MAPTKDM4EHPGD | |
| SCHEMBL16669588 | 0.73 | TLR9 (0.49) | ALOX5 | |
| SCHEMBL430257 | 0.70 | ALOX5 (0.51) | ALOX5ALDH1A1MAPTKDM4EHPGD | |
| SCHEMBL9729530 | 0.70 | ALOX5 (0.54) | PTGS2ALOX5ALDH1A1MAPTKDM4E | |
| SCHEMBL31544361 | 0.70 | ALOX5 (0.54) | PTGS2ALOX5ALDH1A1MAPTKDM4E | |
| SCHEMBL949460 | 0.69 | MAOB (0.51) | ALOX5ALDH1A1MAPTHPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003028762-A1 | NOVEL ANTIMICROBIAL RESISTANCE BLOCKING COMPOSITIONS | ETHICON, INC. (US) | 2003-04-10 | — | — | WO | disclosed |