Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 7/20 | 0.51 |
| ▸ | MAOA | P21397 | 4/20 | 0.51 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | GRM5 | P41594 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.46 |
| ▸ | RELA | Q04206 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | CA5A | P35218 | 2/20 | 0.44 |
| ▸ | EDNRB | P24530 | 2/20 | 0.42 |
| ▸ | EDNRA | P25101 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4549090 | 0.86 | MAOB (0.47) | MAOBMAOAALOX5NPSR1NPC1 | |
| SCHEMBL2688515 | 0.84 | MAOB (0.53) | MAOBMAOAALOX5NPSR1NPC1 | |
| SCHEMBL12946430 | 0.81 | ALOX5 (0.43) | MAOBALOX5NPC1ALDH1A1NFKB1 | |
| SCHEMBL24215086 | 0.79 | MAOB (0.45) | MAOBMAOAALOX5NPSR1NPC1 | |
| SCHEMBL952469 | 0.78 | NR1H4 (0.54) | MAOBALOX5NPC1ALDH1A1NFKB1 | |
| SCHEMBL1962780 | 0.78 | MAOB (0.51) | MAOBMAOAALOX5NPSR1NPC1 | |
| SCHEMBL2937052 | 0.77 | RARA (0.40) | MAOBMAOAALOX5ALDH1A1MAPT | |
| SCHEMBL953280 | 0.76 | NPSR1 (0.47) | MAOBMAOAALOX5NPSR1NPC1 | |
| SCHEMBL1961908 | 0.76 | MAOB (0.54) | MAOBMAOAALOX5NPSR1NPC1 | |
| SCHEMBL4549091 | 0.76 | MAOB (0.43) | MAOBMAOAALOX5NPSR1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7875736-B2 | catalytic metathesis ring closing; 1,4-benzyloxy-2-hydroxybenzaldehyde reacts with mixture of methyl triphenyl phosphonium bromide and potassium tert-butoxide, followed by reaction with 2-bromo-4'-methoxyacetophenone | KAOHSIUNG MEDICAL UNIVERSITY (TW) | 2011-01-25 | — | — | US | claimed |
| US-20100298582-A1 | Intermediate Compounds and Processes for the Preparation of 7-benzyloxy-3-(4-methoxyphenyl)-2H-1-benzopyran | KAOHSIUNG MEDICAL UNIVERSITY (TW) | 2010-11-25 | — | — | US | claimed |
| US-7875735-B2 | such as haginin E, equol, daidzein, formononetin; dealkylation, hydroboration, oxidation in presence of base, oxidation-dehydrogenation using 2,3-dichloro-5,6-dicyanobenzoquinone, and deprotecting | KAOHSIUNG MEDICAL UNIVERSITY (TW) | 2011-01-25 | — | — | US | disclosed |
| US-7875736-B2 | catalytic metathesis ring closing; 1,4-benzyloxy-2-hydroxybenzaldehyde reacts with mixture of methyl triphenyl phosphonium bromide and potassium tert-butoxide, followed by reaction with 2-bromo-4'-methoxyacetophenone | KAOHSIUNG MEDICAL UNIVERSITY (TW) | 2011-01-25 | — | — | US | disclosed |
| US-7875736-B2 | catalytic metathesis ring closing; 1,4-benzyloxy-2-hydroxybenzaldehyde reacts with mixture of methyl triphenyl phosphonium bromide and potassium tert-butoxide, followed by reaction with 2-bromo-4'-methoxyacetophenone | KAOHSIUNG MEDICAL UNIVERSITY (TW) | 2011-01-25 | — | — | US | disclosed |
| US-7875736-B2 | catalytic metathesis ring closing; 1,4-benzyloxy-2-hydroxybenzaldehyde reacts with mixture of methyl triphenyl phosphonium bromide and potassium tert-butoxide, followed by reaction with 2-bromo-4'-methoxyacetophenone | KAOHSIUNG MEDICAL UNIVERSITY (TW) | 2011-01-25 | — | — | US | disclosed |
| US-7875735-B2 | such as haginin E, equol, daidzein, formononetin; dealkylation, hydroboration, oxidation in presence of base, oxidation-dehydrogenation using 2,3-dichloro-5,6-dicyanobenzoquinone, and deprotecting | KAOHSIUNG MEDICAL UNIVERSITY (TW) | 2011-01-25 | — | — | US | disclosed |
| US-7875735-B2 | such as haginin E, equol, daidzein, formononetin; dealkylation, hydroboration, oxidation in presence of base, oxidation-dehydrogenation using 2,3-dichloro-5,6-dicyanobenzoquinone, and deprotecting | KAOHSIUNG MEDICAL UNIVERSITY (TW) | 2011-01-25 | — | — | US | disclosed |
| US-7875735-B2 | such as haginin E, equol, daidzein, formononetin; dealkylation, hydroboration, oxidation in presence of base, oxidation-dehydrogenation using 2,3-dichloro-5,6-dicyanobenzoquinone, and deprotecting | KAOHSIUNG MEDICAL UNIVERSITY (TW) | 2011-01-25 | — | — | US | disclosed |
| US-7875736-B2 | catalytic metathesis ring closing; 1,4-benzyloxy-2-hydroxybenzaldehyde reacts with mixture of methyl triphenyl phosphonium bromide and potassium tert-butoxide, followed by reaction with 2-bromo-4'-methoxyacetophenone | KAOHSIUNG MEDICAL UNIVERSITY (TW) | 2011-01-25 | — | — | US | disclosed |
| US-20100298581-A1 | Processes for Preparing Isoflavonoids using 7-benzyloxy-3-(4-methoxyphenyl)-2H-1-benzopyran as a Starting Material | KAOHSIUNG MEDICAL UNIVERSITY (TW) | 2010-11-25 | — | — | US | disclosed |
| US-20100298581-A1 | Processes for Preparing Isoflavonoids using 7-benzyloxy-3-(4-methoxyphenyl)-2H-1-benzopyran as a Starting Material | KAOHSIUNG MEDICAL UNIVERSITY (TW) | 2010-11-25 | — | — | US | disclosed |
| US-20100298581-A1 | Processes for Preparing Isoflavonoids using 7-benzyloxy-3-(4-methoxyphenyl)-2H-1-benzopyran as a Starting Material | KAOHSIUNG MEDICAL UNIVERSITY (TW) | 2010-11-25 | — | — | US | disclosed |
| US-20100298582-A1 | Intermediate Compounds and Processes for the Preparation of 7-benzyloxy-3-(4-methoxyphenyl)-2H-1-benzopyran | KAOHSIUNG MEDICAL UNIVERSITY (TW) | 2010-11-25 | — | — | US | disclosed |
| US-20100298582-A1 | Intermediate Compounds and Processes for the Preparation of 7-benzyloxy-3-(4-methoxyphenyl)-2H-1-benzopyran | KAOHSIUNG MEDICAL UNIVERSITY (TW) | 2010-11-25 | — | — | US | disclosed |
| US-20100298581-A1 | Processes for Preparing Isoflavonoids using 7-benzyloxy-3-(4-methoxyphenyl)-2H-1-benzopyran as a Starting Material | KAOHSIUNG MEDICAL UNIVERSITY (TW) | 2010-11-25 | — | — | US | disclosed |
| US-20100298582-A1 | Intermediate Compounds and Processes for the Preparation of 7-benzyloxy-3-(4-methoxyphenyl)-2H-1-benzopyran | KAOHSIUNG MEDICAL UNIVERSITY (TW) | 2010-11-25 | — | — | US | disclosed |
| US-20100298582-A1 | Intermediate Compounds and Processes for the Preparation of 7-benzyloxy-3-(4-methoxyphenyl)-2H-1-benzopyran | KAOHSIUNG MEDICAL UNIVERSITY (TW) | 2010-11-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100298582-A1 | Intermediate Compounds and Processes for the Preparation of 7-benzyloxy-3-(4-methoxyphenyl)-2H-1-benzopyran | CYP11B1, CYP2E1, CYP1B1 | MAOB 80/4885MAOA 100/4885ALOX5 1539/4885 |
| US-20100298581-A1 | Processes for Preparing Isoflavonoids using 7-benzyloxy-3-(4-methoxyphenyl)-2H-1-benzopyran as a Starting Material | EGLN2, HABP2, CYP8B1 | MAOB 1773/4885MAOA 2622/4885ALOX5 1011/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.