Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | HTR1D | P28221 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | HTR1A | P08908 | 6/20 | 0.38 |
| ▸ | HTR6 | P50406 | 2/20 | 0.36 |
| ▸ | MPO | P05164 | 1/20 | 0.36 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.34 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.34 |
| ▸ | HTR1B | P28222 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7059150 | 0.81 | HTR1A (0.41) | ALDH1A1KDM4ETDP1HTR1DMAPT | |
| SCHEMBL10695894 | 0.80 | TAAR1 (0.38) | ALDH1A1MAPTPOLBGPR55GAA | |
| SCHEMBL8056096 | 0.79 | TAAR1 (0.55) | ALDH1A1KDM4ETDP1HTR1DMAPT | |
| SCHEMBL10358948 | 0.78 | ALDH1A1 (0.49) | ALDH1A1KDM4ETDP1HTR1DMAPT | |
| SCHEMBL7057929 | 0.73 | HTR6 (0.44) | ALDH1A1KDM4EMAPTPOLBHTR6 | |
| SCHEMBL16039694 | 0.71 | CSNK2A1 (0.42) | ALDH1A1KDM4EHTR1DMAPT | |
| SCHEMBL8516081 | 0.68 | ALDH1A1 (0.44) | ALDH1A1KDM4ETDP1MAPTGAA | |
| SCHEMBL7890533 | 0.68 | TACR1 (0.54) | ALDH1A1KDM4ETDP1MAPTPOLB | |
| SCHEMBL30618212 | 0.68 | ALDH1A1 (0.44) | ALDH1A1KDM4ETDP1MAPTGAA | |
| SCHEMBL8093819 | 0.66 | KCNH2 (0.51) | HTR1AADRA2ASLC6A4ADRA1ADRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0955806-B1 | BIOACTIVE COMPOUNDS | US AGRICULTURE (US) | 2003-05-14 | — | — | EP | disclosed |
| EP-0955806-A4 | BIOACTIVE COMPOUNDS | US AGRICULTURE (US) | 2000-05-31 | — | — | EP | disclosed |
| EP-0955806-A1 | BIOACTIVE COMPOUNDS | THE UNITED STATES OF AMERICA as represented by THE SECRETARY OF AGRICULTURE (US) | 1999-11-17 | — | — | EP | disclosed |
| WO-1997031529-A1 | BIOACTIVE COMPOUNDS | THE UNITED STATES OF AMERICA, REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) | 1997-09-04 | — | — | WO | disclosed |