Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 6/20 | 0.41 |
| ▸ | HTR6 | P50406 | 2/20 | 0.41 |
| ▸ | HTR1D | P28221 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | PSEN1 | P49768 | 4/20 | 0.39 |
| ▸ | PSEN2 | P49810 | 4/20 | 0.39 |
| ▸ | APH1B | Q8WW43 | 4/20 | 0.39 |
| ▸ | NCSTN | Q92542 | 4/20 | 0.39 |
| ▸ | APH1A | Q96BI3 | 4/20 | 0.39 |
| ▸ | PSENEN | Q9NZ42 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | MPO | P05164 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 2/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6831444 | 0.82 | HTR6 (0.39) | HTR1AHTR6PSEN1PSEN2APH1B | |
| SCHEMBL7059157 | 0.81 | ALDH1A1 (0.41) | HTR1AHTR6HTR1DLMNAALDH1A1 | |
| SCHEMBL8056096 | 0.80 | TAAR1 (0.55) | HTR1AHTR6HTR1DLMNAALDH1A1 | |
| SCHEMBL30150898 | 0.77 | AMY1A (0.43) | ALDH1A1TDP1TAAR1 | |
| SCHEMBL233241 | 0.77 | AMY1A (0.43) | ALDH1A1TDP1TAAR1 | |
| SCHEMBL10358948 | 0.76 | ALDH1A1 (0.49) | HTR1AHTR6HTR1DALDH1A1KDM4E | |
| SCHEMBL16039694 | 0.76 | CSNK2A1 (0.42) | HTR1DALDH1A1KDM4EMAPT | |
| SCHEMBL12509537 | 0.75 | AMY1A (0.39) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL8142729 | 0.74 | AMY1A (0.38) | LMNAPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL12345571 | 0.73 | AMY1A (0.41) | PSEN1PSEN2APH1BNCSTNAPH1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0955806-B1 | BIOACTIVE COMPOUNDS | US AGRICULTURE (US) | 2003-05-14 | — | — | EP | disclosed |
| EP-0955806-A4 | BIOACTIVE COMPOUNDS | US AGRICULTURE (US) | 2000-05-31 | — | — | EP | disclosed |
| EP-0955806-A1 | BIOACTIVE COMPOUNDS | THE UNITED STATES OF AMERICA as represented by THE SECRETARY OF AGRICULTURE (US) | 1999-11-17 | — | — | EP | disclosed |
| WO-1997031529-A1 | BIOACTIVE COMPOUNDS | THE UNITED STATES OF AMERICA, REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) | 1997-09-04 | — | — | WO | disclosed |