Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 13/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 13/20 | 0.43 |
| ▸ | CLK4 | Q9HAZ1 | 7/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 6/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 7/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 5/20 | 0.41 |
| ▸ | TSHR | P16473 | 4/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HBB | P68871 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7280290 | 0.78 | GBA1 (0.58) | CYP1A2CYP3A4CLK4CYP2C19HSD17B10 | |
| SCHEMBL7439916 | 0.73 | KDM4E (0.45) | CYP1A2CYP3A4CLK4HSD17B10KDM4E | |
| SCHEMBL2804685 | 0.72 | PDE5A (0.70) | PDE5A | |
| SCHEMBL7615723 | 0.69 | LATS1 (0.66) | MAPK1KDM4ETSHRALDH1A1MEN1 | |
| SCHEMBL7611242 | 0.66 | GBA1 (0.62) | CYP1A2CYP3A4CLK4KDM4ETSHR | |
| SCHEMBL5081902 | 0.66 | HTR3A (0.45) | CYP1A2CYP3A4CYP2C19MAPK1HSD17B10 | |
| SCHEMBL432071 | 0.65 | PDE5A (0.62) | KDM4EALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL3642126 | 0.63 | SMPD3 (0.47) | CYP1A2CYP3A4CYP2C19MAPK1KDM4E | |
| SCHEMBL13975721 | 0.63 | TLR7 (0.57) | — | |
| SCHEMBL7280666 | 0.63 | HTT (0.44) | CYP1A2CYP3A4CLK4CYP2C19MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1307184-A2 | DRUGS FOR INCONTINENCE | NICOX S.A. (FR) | 2003-05-07 | — | — | EP | claimed |
| WO-2002011707-A2 | DRUGS FOR INCONTINENCE | NICOX S.A. (FR) | 2002-02-14 | — | — | WO | claimed |
| EP-1307184-A2 | DRUGS FOR INCONTINENCE | NICOX S.A. (FR) | 2003-05-07 | — | — | EP | disclosed |
| WO-2002011707-A2 | DRUGS FOR INCONTINENCE | NICOX S.A. (FR) | 2002-02-14 | — | — | WO | disclosed |