Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A known ✓ | Q15858 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.37 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.37 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.37 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.37 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1680138 | 0.96 | ALDH1A1 (0.44) | ALDH1A1KDM4EMEN1MAPTKMT2A | |
| SCHEMBL1762653 | 0.83 | ALDH1A1 (0.42) | ALDH1A1KDM4EMEN1KMT2APDE4B | |
| SCHEMBL354326 | 0.83 | KDM4E (0.45) | ALDH1A1KDM4EMEN1MAPTKMT2A | |
| SCHEMBL1762446 | 0.82 | ALDH1A1 (0.48) | ALDH1A1KDM4EMAPTL3MBTL1PDE4B | |
| SCHEMBL951462 | 0.82 | SMN1; SMN2 (0.52) | ALDH1A1KDM4EMEN1MAPTKMT2A | |
| SCHEMBL29558577 | 0.82 | ALDH1A1 (0.48) | ALDH1A1KDM4EMAPTL3MBTL1PDE4B | |
| SCHEMBL950958 | 0.81 | ALDH1A1 (0.47) | ALDH1A1KDM4EMEN1MAPTKMT2A | |
| SCHEMBL29860005 | 0.81 | ALDH1A1 (0.47) | ALDH1A1KDM4EMEN1MAPTKMT2A | |
| SCHEMBL24947591 | 0.81 | ALDH1A1 (0.39) | ALDH1A1KDM4EMEN1KMT2APDE4B | |
| SCHEMBL30206585 | 0.81 | ALDH1A1 (0.39) | ALDH1A1KDM4EMEN1KMT2APDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1427285-A1 | ANTHRANILAMIDE ARTHROPODICIDE TREATMENT | E. I. du Pont de Nemours and Company (US) | 2004-06-16 | — | — | EP | disclosed |
| WO-2003024222-A1 | ANTHRANILAMIDE ARTHROPODICIDE TREATMENT | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2003-03-27 | — | — | WO | disclosed |