Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 5/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.40 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.39 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.39 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.38 |
| ▸ | KLKB1 | P03952 | 2/20 | 0.38 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | RXRA | P19793 | 1/20 | 0.36 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.36 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.36 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL535347 | 0.89 | KLKB1 (0.49) | KDM4EMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL114535 | 0.89 | KDM4E (0.49) | KDM4EMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL30863652 | 0.89 | KDM4E (0.49) | KDM4EMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL29488448 | 0.88 | KDM4E (0.48) | KDM4EMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL15272015 | 0.88 | KDM4E (0.48) | KDM4EMEN1ALDH1A1MAPTKMT2A | |
| Hydrochloric Acid SCHEMBL536232 | 0.88 | KLKB1 (0.48) | KDM4EMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL1680138 | 0.86 | ALDH1A1 (0.44) | KDM4EMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL21021015 | 0.86 | KDM4E (0.46) | KDM4EMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL12911841 | 0.83 | KDM4E (0.50) | KDM4EMEN1ALDH1A1MAPTKMT2A | |
| Sulfuric Acid SCHEMBL7059889 | 0.83 | ALDH1A1 (0.41) | KDM4EMEN1ALDH1A1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2064196-B1 | 3-AMINO-1,2-BENZISOTHIAZOLE COMPOUNDS FOR COMBATING ANIMAL PEST II | BASF SE (DE) | 2012-03-14 | — | — | EP | disclosed |