Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 3/20 | 0.51 |
| ▸ | CASR | P41180 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.35 |
| ▸ | OGG1 | O15527 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.31 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.31 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.31 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL697512 | 1.00 | CYP19A1 (0.51) | CYP19A1CASRNPC1RAB9ACYP3A4 | |
| SCHEMBL697816 | 0.88 | CYP19A1 (0.51) | CYP19A1CASRNPC1RAB9ACYP3A4 | |
| SCHEMBL11531941 | 0.85 | CYP19A1 (0.62) | CYP19A1CASRNPC1RAB9ACYP3A4 | |
| SCHEMBL27733474 | 0.83 | CYP19A1 (0.47) | CYP19A1NPC1RAB9ACYP3A4MAPK1 | |
| SCHEMBL698443 | 0.83 | CYP19A1 (0.40) | CYP19A1CYP3A4MAPK1ALDH1A1CYP1A2 | |
| SCHEMBL6299558 | 0.82 | CYP19A1 (0.46) | CYP19A1CASRRAB9ACYP3A4MAPK1 | |
| SCHEMBL696482 | 0.79 | CYP19A1 (0.44) | CYP19A1NPC1RAB9AALDH1A1MDM2 | |
| SCHEMBL11137594 | 0.79 | CYP19A1 (0.48) | CYP19A1CASRNPC1RAB9ACYP3A4 | |
| SCHEMBL11532106 | 0.78 | CYP19A1 (0.61) | CYP19A1CASRNPC1RAB9ACYP3A4 | |
| SCHEMBL697717 | 0.77 | CYP19A1 (0.51) | CYP19A1CYP3A4MDM2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6207695-B1 | INHIBITING GROWTH OF FUNGUS IN ASSOCIATION WITH A PLANT COMPRISING APPLYING TO THE LOCUS OF A PLANT A FUNGICIDALLY EFFECTIVE AMOUNT OF THE (S)-ENANTIOMER OF 1-(2-(2,4-DICHLOROPHENYL)-2-(2-PROPENYLOXY)ETHYL)-1H-IMIDAZOLE | CELGENE CORPORATION | 2001-03-27 | — | — | US | disclosed |