Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A2 | P43004 | 2/20 | 0.48 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.48 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.44 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.43 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.43 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.43 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.41 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.41 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.41 |
| ▸ | DPP4 | P27487 | 1/20 | 0.41 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.41 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5296286 | 0.98 | SLC1A2 (0.50) | SLC1A2SLC1A1SLC1A3CA2MAPK1 | |
| SCHEMBL31370048 | 0.98 | SLC1A2 (0.50) | SLC1A2SLC1A1SLC1A3CA2MAPK1 | |
| SCHEMBL8666519 | 0.98 | SLC1A2 (0.50) | SLC1A2SLC1A1SLC1A3CA2MAPK1 | |
| Hydrochloric Acid SCHEMBL7058777 | 0.96 | SLC1A2 (0.48) | SLC1A2SLC1A1SLC1A3CA2MAPK1 | |
| SCHEMBL28832535 | 0.92 | GPR84 (0.52) | SLC1A2SLC1A1GRIK1GRIK2ACE2 | |
| SCHEMBL28727358 | 0.92 | GPR84 (0.52) | SLC1A2SLC1A1GRIK1GRIK2ACE2 | |
| SCHEMBL7054887 | 0.92 | GPR84 (0.52) | SLC1A2SLC1A1GRIK1GRIK2ACE2 | |
| SCHEMBL4544292 | 0.92 | GRIK1 (0.52) | SLC1A2SLC1A1SLC1A3SLC7A5GRIK1 | |
| SCHEMBL4544294 | 0.92 | GRIK1 (0.52) | SLC1A2SLC1A1SLC1A3SLC7A5GRIK1 | |
| SCHEMBL7080471 | 0.90 | GPR84 (0.53) | SLC1A2SLC1A1GRIK1GRIK2ACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030229145-A1 | Pain treatment methods and compositions | GRUENENTHAL GMBH (DE) | 2003-12-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030229145-A1 | Pain treatment methods and compositions | AADAT, BCAT2, BCAT1 | SLC1A2 10/4885SLC1A1 16/4885SLC1A3 34/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.