Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMURF2 | Q9HAU4 | 1/20 | 0.38 |
| ▸ | SMURF1 | Q9HCE7 | 1/20 | 0.38 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.36 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.36 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | PPARD | Q03181 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.34 |
| ▸ | NR1H4 | Q96RI1 | 5/20 | 0.34 |
| ▸ | STAT3 | P40763 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | FABP4 | P15090 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8492440 | 0.89 | NR1H4 (0.38) | GPBAR1RAB9ASMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL27500065 | 0.86 | ALDH1A1 (0.35) | SMURF2SMURF1GPBAR1RAB9ASMN1; SMN2 | |
| SCHEMBL8761934 | 0.84 | PTGDR2 (0.37) | RAB9ASMN1; SMN2ALDH1A1HPGDCASP3 | |
| SCHEMBL8492682 | 0.83 | SMURF2 (0.40) | SMURF2SMURF1GPBAR1RAB9ASMN1; SMN2 | |
| SCHEMBL8762913 | 0.82 | SMURF2 (0.38) | SMURF2SMURF1GPBAR1RAB9APPARG | |
| SCHEMBL8763732 | 0.81 | SMURF2 (0.37) | SMURF2SMURF1GPBAR1RAB9ASMN1; SMN2 | |
| SCHEMBL7060912 | 0.80 | SMURF2 (0.38) | SMURF2SMURF1GPBAR1RAB9ASMN1; SMN2 | |
| SCHEMBL8762915 | 0.80 | NR1H4 (0.44) | SMURF2SMURF1GPBAR1PPARGPPARD | |
| SCHEMBL8763702 | 0.80 | SMN1; SMN2 (0.42) | RAB9ASMN1; SMN2ALDH1A1HPGDNPC1 | |
| SCHEMBL27526689 | 0.79 | PTGDR2 (0.37) | SMURF2SMURF1GPBAR1SMN1; SMN2PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0487357-B1 | 4 Benzoyl isoxazole derivatives | RHONE POULENC AGRICULTURE (GB) | 1997-07-02 | — | — | EP | claimed |