Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMURF2 | Q9HAU4 | 1/20 | 0.38 |
| ▸ | SMURF1 | Q9HCE7 | 1/20 | 0.38 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.34 |
| ▸ | NR1H4 | Q96RI1 | 16/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | FABP1 | P07148 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8494843 | 0.86 | NPC1 (0.38) | NR1H4 | |
| SCHEMBL8762928 | 0.84 | SMURF2 (0.36) | SMURF2SMURF1GPBAR1NR1H4 | |
| SCHEMBL8762846 | 0.83 | LMNA (0.42) | SMURF2SMURF1NR1H4LMNA | |
| SCHEMBL7060912 | 0.82 | SMURF2 (0.38) | SMURF2SMURF1GPBAR1NR1H4FABP1 | |
| SCHEMBL8762913 | 0.81 | SMURF2 (0.38) | SMURF2SMURF1GPBAR1NR1H4 | |
| SCHEMBL8822184 | 0.80 | SMURF2 (0.37) | SMURF2SMURF1GPBAR1NR1H4FABP1 | |
| SCHEMBL8588447 | 0.80 | NR1H4 (0.33) | NR1H4 | |
| SCHEMBL8762848 | 0.80 | NR1H4 (0.35) | SMURF2SMURF1GPBAR1NR1H4 | |
| SCHEMBL8822199 | 0.79 | NPC1 (0.34) | GPBAR1NR1H4 | |
| SCHEMBL8763780 | 0.78 | BCAT2 (0.39) | SMURF2SMURF1GPBAR1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0560482-B1 | 4-Benzoyl isoxazole derivatives and their use as herbicides | RHONE POULENC AGRICULTURE (GB) | 1997-08-06 | — | — | EP | claimed |