Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB4 | P30926 | 5/20 | 0.46 |
| ▸ | CHRNA3 | P32297 | 5/20 | 0.46 |
| ▸ | ACKR3 | P25106 | 4/20 | 0.41 |
| ▸ | UHRF1 | Q96T88 | 1/20 | 0.41 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7061352 | 0.85 | CHRM3 (0.48) | ACKR3 | |
| SCHEMBL7062275 | 0.77 | SIGMAR1 (0.44) | — | |
| SCHEMBL12314795 | 0.75 | CHRNB4 (0.45) | CHRNB4CHRNA3 | |
| SCHEMBL194099 | 0.75 | CHRNB4 (0.45) | CHRNB4CHRNA3 | |
| SCHEMBL7061296 | 0.74 | HTR6 (0.49) | CHRNB4CHRNA3 | |
| Hydrochloric Acid SCHEMBL6333252 | 0.74 | ESRRG (0.44) | CHRNB4CHRNA3 | |
| SCHEMBL7161658 | 0.72 | CHRNB2 (0.45) | CHRNB4CHRNA3 | |
| SCHEMBL11458219 | 0.72 | CHRNB4 (0.56) | CHRNB4CHRNA3EHMT2 | |
| SCHEMBL19461951 | 0.70 | CHRNB4 (0.57) | CHRNB4CHRNA3EHMT2 | |
| SCHEMBL11458400 | 0.70 | CHRNB4 (0.54) | CHRNB4CHRNA3EHMT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0874818-B1 | NOVEL SUBSTITUTED ARYL COMPOUNDS USEFUL AS MODULATORS OF ACETYLCHOLINE RECEPTORS | MERCK & CO INC (US) | 2003-05-21 | — | — | EP | disclosed |
| US-6316490-B1 | FOR THERAPY OF PARKINSON'S DISEASE, ALZHEIMER'S DISEASE, DEMENTIA, CONTROLLING PAIN | MERCK & CO., INC. | 2001-11-13 | — | — | US | disclosed |