Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 8/20 | 0.40 |
| ▸ | CA12 | O43570 | 5/20 | 0.39 |
| ▸ | CA2 | P00918 | 5/20 | 0.39 |
| ▸ | CA9 | Q16790 | 4/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | DRD1 | P21728 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | HTR2B | P41595 | 1/20 | 0.37 |
| ▸ | CCR2 | P41597 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8728324 | 0.77 | ALDH1A1 (0.31) | CHRM2HSD17B10ABCB11ALDH1A1NR3C1 | |
| SCHEMBL21634029 | 0.75 | ALDH1A1 (0.47) | HSD17B10ABCB11ALDH1A1NR3C1CYP1A2 | |
| Acetic Acid SCHEMBL8076699 | 0.74 | OPRD1 (0.36) | KDM4E | |
| SCHEMBL18575559 | 0.74 | CA12 (0.54) | CHRM2CA12CA2CA9HSD17B10 | |
| SCHEMBL479451 | 0.72 | P2RY6 (0.50) | CHRM2CA12CA2CA9ALDH1A1 | |
| Ethane SCHEMBL27493264 | 0.72 | ALDH1A1 (0.44) | HSD17B10ABCB11ALDH1A1NR3C1CYP1A2 | |
| SCHEMBL3923943 | 0.71 | ALDH1A1 (0.41) | HSD17B10ABCB11ALDH1A1NR3C1CYP1A2 | |
| SCHEMBL7195622 | 0.70 | ALDH1A1 (0.50) | HSD17B10ABCB11ALDH1A1NR3C1CYP1A2 | |
| SCHEMBL4919388 | 0.70 | CHRM2 (0.73) | CHRM2CA12CA2CYP3A4TSHR | |
| SCHEMBL4909307 | 0.70 | CHRM2 (0.73) | CHRM2CA12CA2CYP3A4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030032073-A1 | Method for diagnosis and therapy of Hodgkin's lymphomas | HEIDER KARL-HEINZ (AT) | 2003-02-13 | — | — | US | disclosed |
| US-6372441-B1 | DETECTING THE EXPRESSION OF THE VARIABLE EXON V10 IN THE CD44 GENE IN A PATIENT OR IN A SAMPLE OBTAINED FROM A PATIENT, WHEREIN THE EXPRESSION OF THE VARIABLE EXON V10 IN THE CD44 GENE INDICATES HODGKIN'S LYMPHOMAS | FORSCHUNGSZENTRUM KARLSRUHE GMBH (DE) | 2002-04-16 | — | — | US | disclosed |