Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.31 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.31 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | DRD1 | P21728 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | HTR2B | P41595 | 1/20 | 0.31 |
| ▸ | CCR2 | P41597 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7061211 | 0.77 | CHRM2 (0.40) | ALDH1A1ABCB11NR3C1CYP1A2CYP3A4 | |
| SCHEMBL21634029 | 0.68 | ALDH1A1 (0.47) | ALDH1A1ABCB11NR3C1CYP1A2CYP3A4 | |
| SCHEMBL8728326 | 0.67 | MIF (0.37) | — | |
| Ethane SCHEMBL27493264 | 0.65 | ALDH1A1 (0.44) | ALDH1A1ABCB11NR3C1CYP1A2CYP3A4 | |
| SCHEMBL28789449 | 0.65 | CARM1 (0.49) | — | |
| SCHEMBL7205397 | 0.65 | REN (0.49) | — | |
| SCHEMBL349212 | 0.65 | ALDH1A1 (0.47) | ALDH1A1ABCB11NR3C1CYP1A2CYP3A4 | |
| SCHEMBL7202171 | 0.64 | MAOA (0.53) | MAOATDP1CHRM2 | |
| SCHEMBL8010573 | 0.64 | LCK (0.40) | CYP1A2HSD17B10 | |
| SCHEMBL7195622 | 0.64 | ALDH1A1 (0.50) | ALDH1A1ABCB11NR3C1CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5714166-A | Bioactive and/or targeted dendrimer conjugates | THE DOW CHEMICAL COMPANY (US) | 1998-02-03 | — | — | US | disclosed |