Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | REN | P00797 | 2/20 | 0.38 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.38 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.38 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.37 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | MIF | P14174 | 2/20 | 0.34 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | G6PC1 | P35575 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL28005843 | 0.92 | REN (0.42) | MAOAMAOBRENCARM1PRMT6 | |
| Acetic Acid SCHEMBL28850624 | 0.88 | REN (0.39) | MAOAMAOBRENCARM1PRMT6 | |
| SCHEMBL28055858 | 0.85 | CARM1 (0.49) | MAOAMAOBCARM1PRMT6PRMT8 | |
| Acetic Acid SCHEMBL28964371 | 0.81 | KEAP1 (0.39) | RENKCNH2SIGMAR1MIF | |
| Acetic Acid SCHEMBL27771245 | 0.77 | CARM1 (0.45) | MAOAMAOBCARM1PRMT6PRMT8 | |
| SCHEMBL11293490 | 0.75 | CARM1 (0.47) | RENCARM1PRMT6PRMT8KCNH2 | |
| SCHEMBL21121016 | 0.73 | CARM1 (0.46) | RENCARM1PRMT6PRMT8KCNH2 | |
| SCHEMBL28789449 | 0.72 | CARM1 (0.49) | RENCARM1PRMT6PRMT8KCNH2 | |
| SCHEMBL8507573 | 0.72 | REN (0.47) | RENCARM1PRMT6PRMT8KCNH2 | |
| SCHEMBL11519645 | 0.70 | CHRM2 (0.53) | MAOACARM1PRMT6PRMT8SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030032073-A1 | Method for diagnosis and therapy of Hodgkin's lymphomas | HEIDER KARL-HEINZ (AT) | 2003-02-13 | — | — | US | disclosed |
| US-6372441-B1 | DETECTING THE EXPRESSION OF THE VARIABLE EXON V10 IN THE CD44 GENE IN A PATIENT OR IN A SAMPLE OBTAINED FROM A PATIENT, WHEREIN THE EXPRESSION OF THE VARIABLE EXON V10 IN THE CD44 GENE INDICATES HODGKIN'S LYMPHOMAS | FORSCHUNGSZENTRUM KARLSRUHE GMBH (DE) | 2002-04-16 | — | — | US | disclosed |