Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R known ✓ | P32245 | 1/20 | 0.35 |
| ▸ | NOS2 known ✓ | P35228 | 1/20 | 0.35 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.45 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.45 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.45 |
| ▸ | G6PC1 | P35575 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | LIMK2 | P53671 | 1/20 | 0.36 |
| ▸ | TSPO | P30536 | 1/20 | 0.35 |
| ▸ | MC5R | P33032 | 1/20 | 0.35 |
| ▸ | MC3R | P41968 | 1/20 | 0.35 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28055858 | 0.91 | CARM1 (0.49) | CARM1PRMT6PRMT8G6PC1CA12 | |
| Acetic Acid SCHEMBL28005843 | 0.87 | REN (0.42) | CARM1PRMT6PRMT8G6PC1CA12 | |
| Acetic Acid SCHEMBL28850624 | 0.83 | REN (0.39) | CARM1PRMT6PRMT8G6PC1CA12 | |
| Acetic Acid SCHEMBL8076704 | 0.79 | MEN1 (0.36) | G6PC1CA12CA9NPC1RAB9A | |
| SCHEMBL7061213 | 0.77 | MAOA (0.39) | CARM1PRMT6PRMT8G6PC1MAOA | |
| Acetic Acid SCHEMBL28964371 | 0.76 | KEAP1 (0.39) | NPC1RAB9AKMT2AMEN1 | |
| Acetic Acid SCHEMBL28784356 | 0.75 | CARM1 (0.56) | CARM1PRMT6PRMT8CA12CA9 | |
| Acetic Acid SCHEMBL2252047 | 0.75 | CARM1 (0.56) | CARM1PRMT6PRMT8CA12CA9 | |
| Acetic Acid SCHEMBL28010133 | 0.75 | CARM1 (0.56) | CARM1PRMT6PRMT8CA12CA9 | |
| Acetic Acid SCHEMBL8440715 | 0.75 | CARM1 (0.56) | CARM1PRMT6PRMT8CA12CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105388280-A | Indirect competitive ELISA kit and detection method for detecting content of mercury in textiles based on mercury monoclonal antibody | JIANGSU ACAD OF SCIENCE AND TECH FOR INSPECTION AND QUARANTINE | 2016-03-09 | — | — | CN | claimed |
| CN-105388280-A | Indirect competitive ELISA kit and detection method for detecting content of mercury in textiles based on mercury monoclonal antibody | JIANGSU ACAD OF SCIENCE AND TECH FOR INSPECTION AND QUARANTINE | 2016-03-09 | — | — | CN | disclosed |
| CN-101655499-A | Indirect competitive enzyme-linked immunosorbent assay for measuring heavy metal mercury | NANJING UNIVERSITY OF TECHNOLOGY | 2010-02-24 | — | — | CN | disclosed |